Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 5064064..5064653 Replicon chromosome
Accession NZ_CP102374
Organism Pseudomonas sp. T8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NRG23_RS22895 Protein ID WP_053270039.1
Coordinates 5064064..5064363 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NRG23_RS22900 Protein ID WP_028683469.1
Coordinates 5064360..5064653 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRG23_RS22865 (NRG23_22865) 5059545..5060432 - 888 WP_038575447.1 (2E,6E)-farnesyl diphosphate synthase -
NRG23_RS22870 (NRG23_22870) 5060429..5060671 - 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
NRG23_RS22875 (NRG23_22875) 5060897..5061988 + 1092 WP_009051081.1 copper-containing nitrite reductase -
NRG23_RS22880 (NRG23_22880) 5062052..5062351 + 300 WP_009051080.1 helix-turn-helix transcriptional regulator -
NRG23_RS22885 (NRG23_22885) 5062409..5063419 + 1011 WP_173424526.1 NAD(P)-dependent alcohol dehydrogenase -
NRG23_RS22890 (NRG23_22890) 5063444..5063893 - 450 WP_009051078.1 DUF3828 domain-containing protein -
NRG23_RS22895 (NRG23_22895) 5064064..5064363 + 300 WP_053270039.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NRG23_RS22900 (NRG23_22900) 5064360..5064653 + 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
NRG23_RS22905 (NRG23_22905) 5064786..5065178 - 393 WP_009051075.1 hypothetical protein -
NRG23_RS22910 (NRG23_22910) 5065550..5066437 - 888 WP_028683471.1 LysR family transcriptional regulator -
NRG23_RS22915 (NRG23_22915) 5066564..5067754 + 1191 WP_028683472.1 serine hydrolase domain-containing protein -
NRG23_RS22920 (NRG23_22920) 5067949..5069112 + 1164 WP_257372261.1 acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11267.01 Da        Isoelectric Point: 10.4277

>T253489 WP_053270039.1 NZ_CP102374:5064064-5064363 [Pseudomonas sp. T8]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT253489 WP_028683469.1 NZ_CP102374:5064360-5064653 [Pseudomonas sp. T8]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References