Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4078581..4079097 Replicon chromosome
Accession NZ_CP102374
Organism Pseudomonas sp. T8

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag NRG23_RS18315 Protein ID WP_257371562.1
Coordinates 4078581..4078862 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag NRG23_RS18320 Protein ID WP_009046356.1
Coordinates 4078852..4079097 (-) Length 82 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRG23_RS18295 (NRG23_18295) 4074843..4075736 - 894 WP_257371557.1 HlyD family secretion protein -
NRG23_RS18300 (NRG23_18300) 4075733..4075942 - 210 WP_007932080.1 DUF1656 domain-containing protein -
NRG23_RS18305 (NRG23_18305) 4075939..4078023 - 2085 WP_257371560.1 FUSC family protein -
NRG23_RS18310 (NRG23_18310) 4078020..4078448 - 429 WP_028681511.1 winged helix DNA-binding protein -
NRG23_RS18315 (NRG23_18315) 4078581..4078862 - 282 WP_257371562.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NRG23_RS18320 (NRG23_18320) 4078852..4079097 - 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NRG23_RS18325 (NRG23_18325) 4079162..4079407 - 246 WP_009046355.1 DUF2789 domain-containing protein -
NRG23_RS18330 (NRG23_18330) 4079538..4079999 - 462 WP_016705004.1 YbaK/EbsC family protein -
NRG23_RS18335 (NRG23_18335) 4080223..4081608 + 1386 WP_009046353.1 nodulation protein NfeD -
NRG23_RS18340 (NRG23_18340) 4081610..4082368 + 759 WP_009046352.1 slipin family protein -
NRG23_RS18345 (NRG23_18345) 4082334..4083329 - 996 WP_257371566.1 sulfotransferase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10826.76 Da        Isoelectric Point: 10.3351

>T253488 WP_257371562.1 NZ_CP102374:c4078862-4078581 [Pseudomonas sp. T8]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RECSAVYERARKR

Download         Length: 282 bp


Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT253488 WP_009046356.1 NZ_CP102374:c4079097-4078852 [Pseudomonas sp. T8]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References