Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1866996..1867581 Replicon chromosome
Accession NZ_CP102374
Organism Pseudomonas sp. T8

Toxin (Protein)


Gene name PumA Uniprot ID A0A7S5HMS4
Locus tag NRG23_RS08140 Protein ID WP_016705075.1
Coordinates 1866996..1867289 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NRG23_RS08145 Protein ID WP_150085183.1
Coordinates 1867291..1867581 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRG23_RS08125 (NRG23_08125) 1862640..1863884 - 1245 WP_028682913.1 M20/M25/M40 family metallo-hydrolase -
NRG23_RS08130 (NRG23_08130) 1863978..1865102 - 1125 WP_257374333.1 diguanylate cyclase -
NRG23_RS08135 (NRG23_08135) 1865367..1866761 + 1395 WP_257374334.1 VOC family protein -
NRG23_RS08140 (NRG23_08140) 1866996..1867289 + 294 WP_016705075.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NRG23_RS08145 (NRG23_08145) 1867291..1867581 + 291 WP_150085183.1 putative addiction module antidote protein Antitoxin
NRG23_RS08150 (NRG23_08150) 1867981..1868568 - 588 WP_009048176.1 hypothetical protein -
NRG23_RS08155 (NRG23_08155) 1868687..1870069 - 1383 WP_257374335.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-97)

Antitoxin

Uncharacterized protein HI1420

(9-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10699.27 Da        Isoelectric Point: 10.0959

>T253482 WP_016705075.1 NZ_CP102374:1866996-1867289 [Pseudomonas sp. T8]
MDYEILQTTVFAQWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGNTLIVLLLGGDK
SSQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10269.80 Da        Isoelectric Point: 8.0096

>AT253482 WP_150085183.1 NZ_CP102374:1867291-1867581 [Pseudomonas sp. T8]
MSDTLVPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKTTGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7S5HMS4

Antitoxin

Source ID Structure

References