253477

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5918263..5918788 Replicon chromosome
Accession NZ_CP102358
Organism Pseudomonas zeae strain BIM B-582

Toxin (Protein)


Gene name relE Uniprot ID A0A7H8GF58
Locus tag NQ186_RS26345 Protein ID WP_016984129.1
Coordinates 5918492..5918788 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4R7UU95
Locus tag NQ186_RS26340 Protein ID WP_016984130.1
Coordinates 5918263..5918502 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ186_RS26315 (NQ186_26315) 5914063..5914524 + 462 WP_007910890.1 GNAT family N-acetyltransferase -
NQ186_RS26320 (NQ186_26320) 5914755..5915405 + 651 WP_064118832.1 DedA family protein -
NQ186_RS26325 (NQ186_26325) 5915410..5916222 + 813 WP_257356263.1 zinc-dependent peptidase -
NQ186_RS26330 (NQ186_26330) 5916335..5916862 + 528 WP_003205933.1 inorganic diphosphatase -
NQ186_RS26335 (NQ186_26335) 5917086..5917832 + 747 WP_093434520.1 helix-turn-helix transcriptional regulator -
NQ186_RS26340 (NQ186_26340) 5918263..5918502 + 240 WP_016984130.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NQ186_RS26345 (NQ186_26345) 5918492..5918788 + 297 WP_016984129.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQ186_RS26350 (NQ186_26350) 5918843..5919655 - 813 WP_257356266.1 DUF2135 domain-containing protein -
NQ186_RS26355 (NQ186_26355) 5919659..5921278 - 1620 WP_257356269.1 DUF2300 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-62)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11651.55 Da        Isoelectric Point: 9.6908

>T253477 WP_016984129.1 NZ_CP102358:5918492-5918788 [Pseudomonas zeae]
MTYNLEFDRRALKEWNKLGDTVRHQFKKKLTEVLENPRIEANRLRELPDCYKVKLKSAGYRLIYQVLDQEIVVFVIAIGK
REREAAYEVAQDRLSLLP

Download         Length: 297 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8865.24 Da        Isoelectric Point: 4.6017

>AT253477 WP_016984130.1 NZ_CP102358:5918263-5918502 [Pseudomonas zeae]
MASINIRIDDDLKQRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKAALLSEEDEVLIAVVTERLAAPQRVKVSLDDL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H8GF58

Antitoxin

Source ID Structure
AlphaFold DB A0A4R7UU95

References