Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicB(antitoxin)
Location 564917..565556 Replicon chromosome
Accession NZ_CP102358
Organism Pseudomonas zeae strain BIM B-582

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NQ186_RS02500 Protein ID WP_095190108.1
Coordinates 564917..565099 (+) Length 61 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NQ186_RS02505 Protein ID WP_257356808.1
Coordinates 565131..565556 (+) Length 142 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ186_RS02465 (NQ186_02465) 560127..560504 + 378 WP_008080517.1 GNAT family N-acetyltransferase -
NQ186_RS02470 (NQ186_02470) 560501..561217 + 717 WP_099757732.1 AzlC family ABC transporter permease -
NQ186_RS02475 (NQ186_02475) 561196..561513 + 318 WP_007909127.1 AzlD domain-containing protein -
NQ186_RS02480 (NQ186_02480) 561430..562356 - 927 WP_093430009.1 LysR family transcriptional regulator -
NQ186_RS02485 (NQ186_02485) 563054..563461 + 408 WP_093430011.1 MbcA/ParS/Xre antitoxin family protein -
NQ186_RS02490 (NQ186_02490) 563473..564138 + 666 WP_257356805.1 RES family NAD+ phosphorylase -
NQ186_RS02495 (NQ186_02495) 564181..564462 - 282 WP_122844308.1 DUF3077 domain-containing protein -
NQ186_RS02500 (NQ186_02500) 564917..565099 + 183 WP_095190108.1 type II toxin-antitoxin system HicA family toxin Toxin
NQ186_RS02505 (NQ186_02505) 565131..565556 + 426 WP_257356808.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NQ186_RS02510 (NQ186_02510) 566162..567406 + 1245 WP_212626030.1 hypothetical protein -
NQ186_RS02515 (NQ186_02515) 567399..568148 + 750 WP_169880155.1 hypothetical protein -
NQ186_RS02520 (NQ186_02520) 568120..570447 + 2328 WP_257356810.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(3-58)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6795.85 Da        Isoelectric Point: 10.7304

>T253472 WP_095190108.1 NZ_CP102358:564917-565099 [Pseudomonas zeae]
MKYSEFRRWLKAQGVEFQNGKGSHFKVSLNGKSTVFPDHGAKEMGEGLRKSIIKQLGLKD

Download         Length: 183 bp

Antitoxin


Download         Length: 142 a.a.        Molecular weight: 15595.75 Da        Isoelectric Point: 4.5890

>AT253472 WP_257356808.1 NZ_CP102358:565131-565556 [Pseudomonas zeae]
MFEYALEVHEEPDSVWLSCAEIPEMHAVGDTLEQALDSAIDAIETALSIYVDDRRLAPTGQAGEQKSDVVLRLPALTAAK
VALWNTLLESGVSKAELARRLGVQRPQVDRLVDFLHHSKIENVERALQQLGRRILLSVEAA

Download         Length: 426 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References