Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2807467..2807986 Replicon chromosome
Accession NZ_CP102330
Organism Burkholderia cepacia strain N3009-2YT

Toxin (Protein)


Gene name relE Uniprot ID A0A2X1HSN6
Locus tag NQK75_RS29365 Protein ID WP_059495132.1
Coordinates 2807467..2807748 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2X1IH73
Locus tag NQK75_RS29370 Protein ID WP_059495134.1
Coordinates 2807738..2807986 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQK75_RS29345 2803197..2803895 - 699 WP_021159681.1 MgtC/SapB family protein -
NQK75_RS29350 2804010..2805119 + 1110 WP_069255048.1 AGE family epimerase/isomerase -
NQK75_RS29355 2805092..2806711 - 1620 WP_257250083.1 methyl-accepting chemotaxis protein -
NQK75_RS29360 2806983..2807426 + 444 WP_059523219.1 PaaI family thioesterase -
NQK75_RS29365 2807467..2807748 - 282 WP_059495132.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQK75_RS29370 2807738..2807986 - 249 WP_059495134.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NQK75_RS29375 2808109..2809161 - 1053 WP_257250084.1 CaiB/BaiF CoA-transferase family protein -
NQK75_RS29380 2809357..2810550 - 1194 WP_059495147.1 2-methylaconitate cis-trans isomerase PrpF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-78)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10928.89 Da        Isoelectric Point: 10.6474

>T253434 WP_059495132.1 NZ_CP102330:c2807748-2807467 [Burkholderia cepacia]
MTFELAFLEPALKEWKKLDRTVRDQFKAKLAERLEHPRIPSAKLHGHPDRYKIKLRGVGYRLVYEVRDAEVIVLVVAVGR
RERDAVYLAAMKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8991.33 Da        Isoelectric Point: 5.0636

>AT253434 WP_059495134.1 NZ_CP102330:c2807986-2807738 [Burkholderia cepacia]
MPHTILASVTASVSELKRNPMGTVAAGEGFPVAILNHNEPAFYCIPAKTWEAMVERLEDIEDNALADSRAREKVVKVKLN
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2X1HSN6

Antitoxin

Source ID Structure
AlphaFold DB A0A2X1IH73

References