Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1724034..1725442 Replicon chromosome
Accession NZ_CP102328
Organism Pseudomonas otitidis strain BC12

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag NRL37_RS08100 Protein ID WP_142011214.1
Coordinates 1724034..1724603 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NRL37_RS08105 Protein ID WP_268194489.1
Coordinates 1724600..1725442 (+) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRL37_RS08090 (NRL37_08090) 1719036..1720235 - 1200 WP_268194488.1 GGDEF domain-containing protein -
NRL37_RS08095 (NRL37_08095) 1720322..1723798 - 3477 WP_182852136.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
NRL37_RS08100 (NRL37_08100) 1724034..1724603 + 570 WP_142011214.1 GNAT family protein Toxin
NRL37_RS08105 (NRL37_08105) 1724600..1725442 + 843 WP_268194489.1 AraC family transcriptional regulator Antitoxin
NRL37_RS08110 (NRL37_08110) 1725480..1726193 + 714 WP_268194490.1 AzlC family ABC transporter permease -
NRL37_RS08115 (NRL37_08115) 1726193..1726522 + 330 WP_044406183.1 AzlD domain-containing protein -
NRL37_RS08120 (NRL37_08120) 1726652..1728526 + 1875 WP_268194491.1 MFS transporter -
NRL37_RS08125 (NRL37_08125) 1728580..1728894 - 315 WP_044406178.1 quaternary ammonium compound efflux SMR transporter SugE -
NRL37_RS08130 (NRL37_08130) 1729058..1730011 - 954 WP_044406176.1 bile acid:sodium symporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(18-149)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21147.17 Da        Isoelectric Point: 7.4044

>T253424 WP_142011214.1 NZ_CP102328:1724034-1724603 [Pseudomonas otitidis]
MFNPQPVTLQRGALRLEPLGEADVSELAALAEANRNELVYMSGPLRPDWYRQGIAQQREGQAVVFAIRLGDRLVGTSRFA
EFMPALPAVEIGWTWLAGSEHGTGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQRAIEKLGAVREGVLRNHRRLAD
GRLDDSVMFSITDHEWPAVKQALEAAFVQ

Download         Length: 570 bp

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31263.49 Da        Isoelectric Point: 9.0216

>AT253424 WP_268194489.1 NZ_CP102328:1724600-1725442 [Pseudomonas otitidis]
MSTGGERTRFWQASALSGVELLHARYIQHRFSPHVHEGYVFTILESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTDVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHCLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGQESQAVALAREVLAARLASPPSLEELAALVGLSPFHFARVFQRATGMPPHAWLKQRRLEQARAMLRSGCAPL
SVAMQLGFADQSHLTRQFKQTYGVGPGEYRTASARSFKTD

Download         Length: 843 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References