253419

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1990190..1990730 Replicon chromosome
Accession NZ_CP102294
Organism Alistipes ihumii AP11

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NQ491_RS08075 Protein ID WP_019246687.1
Coordinates 1990431..1990730 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NQ491_RS08070 Protein ID WP_019246688.1
Coordinates 1990190..1990438 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ491_RS08050 (NQ491_08050) 1986158..1986613 - 456 WP_147524764.1 hypothetical protein -
NQ491_RS08055 (NQ491_08055) 1986778..1987341 - 564 WP_147524763.1 hypothetical protein -
NQ491_RS08060 (NQ491_08060) 1988378..1988701 + 324 WP_019246690.1 hypothetical protein -
NQ491_RS08065 (NQ491_08065) 1989125..1990036 + 912 WP_187119335.1 hypothetical protein -
NQ491_RS08070 (NQ491_08070) 1990190..1990438 + 249 WP_019246688.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NQ491_RS08075 (NQ491_08075) 1990431..1990730 + 300 WP_019246687.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQ491_RS08080 (NQ491_08080) 1991064..1991348 + 285 WP_019246686.1 hypothetical protein -
NQ491_RS08085 (NQ491_08085) 1991740..1992102 + 363 WP_019246685.1 hypothetical protein -
NQ491_RS08090 (NQ491_08090) 1992105..1994744 + 2640 WP_019246684.1 PL29 family lyase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1988378..1996539 8161


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11660.37 Da        Isoelectric Point: 7.3808

>T253419 WP_019246687.1 NZ_CP102294:1990431-1990730 [Alistipes ihumii AP11]
MAEYRFTRKAVEDLSDIWHYTLETWSQKQADRYYRMLIECCRNIAEHPLAGRHYAEMAEGVYGLRAGKHIVFYRIAAPNE
IEVIRILHGSMDLKTRVGE

Download         Length: 300 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9103.20 Da        Isoelectric Point: 6.4672

>AT253419 WP_019246688.1 NZ_CP102294:1990190-1990438 [Alistipes ihumii AP11]
MRRNTSVSLGSYFEAFVENKITQGRYKNASEVIRAGLRLLEEEEHRIAVLKNAIQEGLDSGVAVDFDPTEHLASLKAARN
NG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References