253400

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 2250270..2250817 Replicon chromosome
Accession NZ_CP102265
Organism Blautia obeum ATCC 29174

Toxin (Protein)


Gene name relE Uniprot ID A0A395X9D1
Locus tag NQ503_RS10900 Protein ID WP_005422163.1
Coordinates 2250536..2250817 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A395X9D2
Locus tag NQ503_RS10895 Protein ID WP_005422165.1
Coordinates 2250270..2250539 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ503_RS10870 (NQ503_10870) 2245411..2246316 - 906 WP_005422173.1 hypothetical protein -
NQ503_RS10875 (NQ503_10875) 2246338..2248101 - 1764 WP_005422171.1 YARHG domain-containing protein -
NQ503_RS10880 (NQ503_10880) 2248126..2248452 - 327 WP_005422170.1 hypothetical protein -
NQ503_RS10885 (NQ503_10885) 2248497..2249645 - 1149 WP_005422168.1 permease-like cell division protein FtsX -
NQ503_RS10890 (NQ503_10890) 2249781..2250107 + 327 WP_044924801.1 helix-turn-helix transcriptional regulator -
NQ503_RS10895 (NQ503_10895) 2250270..2250539 + 270 WP_005422165.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NQ503_RS10900 (NQ503_10900) 2250536..2250817 + 282 WP_005422163.1 type II toxin-antitoxin system YafQ family toxin Toxin
NQ503_RS10905 (NQ503_10905) 2251083..2255315 - 4233 WP_022388823.1 2-hydroxyacyl-CoA dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10991.74 Da        Isoelectric Point: 9.3370

>T253400 WP_005422163.1 NZ_CP102265:2250536-2250817 [Blautia obeum ATCC 29174]
MKYSIKPTSKFQKDLKRIQKRGYDLSLLSDVIKKLSNGESLPLKYRDHNLIGNFCGCRECHITPDWLLIYEIYEKDLYLY
LTRTGSHSDLFSK

Download         Length: 282 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10363.00 Da        Isoelectric Point: 4.8896

>AT253400 WP_005422165.1 NZ_CP102265:2250270-2250539 [Blautia obeum ATCC 29174]
MANISIRMEDKLKQQAEELFSDLGMNLTTAITIFVKQSIREQRIPFEITRETLNRETLAALREVEKMKRNPSLGKSFDDV
DTMMEDLLK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A395X9D1

Antitoxin

Source ID Structure
AlphaFold DB A0A395X9D2

References