Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 3157401..3158198 Replicon chromosome
Accession NZ_CP102247
Organism Enterobacter asburiae strain R_A5.MM

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag NQ230_RS15080 Protein ID WP_121425842.1
Coordinates 3157401..3157922 (-) Length 174 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag NQ230_RS15085 Protein ID WP_257258090.1
Coordinates 3157929..3158198 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQ230_RS15050 (NQ230_15050) 3152997..3153686 + 690 WP_257258087.1 pyrimidine utilization protein B -
NQ230_RS15055 (NQ230_15055) 3153698..3154084 + 387 WP_010429508.1 pyrimidine utilization protein C -
NQ230_RS15060 (NQ230_15060) 3154092..3154892 + 801 WP_159513848.1 pyrimidine utilization protein D -
NQ230_RS15065 (NQ230_15065) 3154902..3155492 + 591 WP_257258088.1 malonic semialdehyde reductase -
NQ230_RS15070 (NQ230_15070) 3155502..3155996 + 495 WP_257258089.1 pyrimidine utilization flavin reductase protein F -
NQ230_RS15075 (NQ230_15075) 3156018..3157340 + 1323 WP_193940031.1 pyrimidine utilization transport protein G -
NQ230_RS15080 (NQ230_15080) 3157401..3157922 - 522 WP_121425842.1 GNAT family N-acetyltransferase Toxin
NQ230_RS15085 (NQ230_15085) 3157929..3158198 - 270 WP_257258090.1 DUF1778 domain-containing protein Antitoxin
NQ230_RS15090 (NQ230_15090) 3158260..3159177 - 918 WP_213821561.1 DMT family transporter -
NQ230_RS15095 (NQ230_15095) 3159294..3159467 - 174 WP_024909630.1 general stress protein -
NQ230_RS15100 (NQ230_15100) 3159858..3160454 + 597 WP_121425840.1 NAD(P)H:quinone oxidoreductase -
NQ230_RS15105 (NQ230_15105) 3160475..3160702 + 228 WP_008499832.1 YccJ family protein -
NQ230_RS15110 (NQ230_15110) 3160736..3161977 - 1242 WP_257258091.1 bifunctional glucose-1-phosphatase/inositol phosphatase -
NQ230_RS15115 (NQ230_15115) 3162130..3162573 + 444 WP_257258092.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(8-86)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19640.38 Da        Isoelectric Point: 6.6400

>T253394 WP_121425842.1 NZ_CP102247:c3157922-3157401 [Enterobacter asburiae]
VANLTIEMLSEGTDYDFEDFDCGEPSLNAFLAEHLVRQHNGRILRAYLLKERDRPRVLGYYTLSGSCFERAMLPSKTQQR
RIPYINVPSVTLGRLAVDKTLQGNEWGTTLVAHAMRVVYLASQAVGVHGIFVDALNEQAKQFYLKQGFIPLTGENSHSLF
FPTKSIERLFEQE

Download         Length: 522 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10261.78 Da        Isoelectric Point: 5.8836

>AT253394 WP_257258090.1 NZ_CP102247:c3158198-3157929 [Enterobacter asburiae]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWNAVMDAIDNPPEPIERLKR
AAKRLRNME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References