Detailed information of TA system TA025337

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 1026385..1026922
• Replicon: chromosome
• Accession: NC_015593
• Organism: Sphingobium chlorophenolicum L-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: SPHCH_RS04765
• Protein ID: WP_013846902.1
• Coordinates: 1026626..1026922 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: SPHCH_RS04760
• Protein ID: WP_013846901.1
• Coordinates: 1026385..1026636 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SPHCH_RS04730	1021409..1022056	-	648	WP_013846895.1	hypothetical protein	-
SPHCH_RS04735	1022132..1022827	-	696	WP_013846896.1	hypothetical protein	-
SPHCH_RS04740	1022969..1023778	-	810	WP_013846897.1	type I restriction-modification system subunit M	-
SPHCH_RS04745	1023945..1025192	-	1248	WP_013846898.1	hypothetical protein	-
SPHCH_RS04750	1025380..1025685	-	306	WP_013846899.1	hypothetical protein	-
SPHCH_RS04755	1025682..1026158	-	477	WP_013846900.1	hypothetical protein	-
SPHCH_RS04760	1026385..1026636	+	252	WP_013846901.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
SPHCH_RS04765	1026626..1026922	+	297	WP_013846902.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	933235..1044714	111479

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-91)

Antitoxin

• Antitoxin ParD (6-75)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10941.43 Da
• Isoelectric Point: 6.8785

>T25337 WP_013846902.1 NC_015593:1026626-1026922 [Sphingobium chlorophenolicum L-1]
MAYRLTRNAEKDLIGIYVGGVGELGEAVAEKYQAGLHRVFGFLSDFPYSARARAEISPPVRAHPYKSHIVVYIIEGQDIL
ILGVRHGREDWQASDQLS

Nucleotide

• Length: 297 bp

>T25337 NC_015593:1026626-1026922 [Sphingobium chlorophenolicum L-1]
ATGGCCTATAGACTCACGCGTAACGCCGAAAAGGATCTCATCGGTATATATGTCGGCGGCGTCGGAGAATTAGGAGAAGC
CGTCGCGGAAAAATATCAGGCCGGTTTGCATCGGGTTTTTGGATTTCTCTCCGACTTTCCCTATTCGGCAAGAGCGCGCG
CGGAAATTTCACCACCGGTCCGGGCACATCCCTACAAGTCCCATATCGTCGTCTATATCATCGAAGGACAGGACATCCTG
ATCCTCGGCGTCCGTCATGGACGGGAAGACTGGCAGGCATCCGACCAGCTTTCCTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9230.40 Da
• Isoelectric Point: 5.8295

>AT25337 WP_013846901.1 NC_015593:1026385-1026636 [Sphingobium chlorophenolicum L-1]
MATMNVSLPDAMKEWVEGQAGTGRYSNASDYVRDLIRRDQERREKIAAMQTMVDESLASGISPNSIDDMMKEARRRAGVG
HGL

Nucleotide

• Length: 252 bp

>AT25337 NC_015593:1026385-1026636 [Sphingobium chlorophenolicum L-1]
ATGGCGACAATGAATGTTTCCCTCCCCGATGCGATGAAGGAATGGGTCGAAGGTCAGGCCGGGACAGGCAGATACAGCAA
TGCCAGCGATTATGTGCGCGACCTGATCCGTCGCGACCAGGAGCGGCGGGAGAAGATCGCAGCCATGCAGACCATGGTCG
ATGAGTCTCTCGCCTCCGGCATAAGTCCCAATTCCATCGATGACATGATGAAGGAAGCCCGGCGTCGCGCAGGCGTCGGT
CATGGCCTATAG