Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2220362..2220630 Replicon chromosome
Accession NZ_CP102244
Organism Escherichia coli O7:H15 strain ST70

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2220489..2220592 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2220362..2220630 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ80_RS10625 2216915..2217577 - 663 WP_000944256.1 exodeoxyribonuclease X -
NQZ80_RS10630 2217601..2218257 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
NQZ80_RS10635 2218359..2218589 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NQZ80_RS10640 2218728..2219102 + 375 WP_001578488.1 CopC domain-containing protein YobA -
NQZ80_RS10645 2219106..2219978 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
NQZ80_RS10650 2219991..2220332 + 342 WP_000976485.1 YebY family protein -
- 2220362..2220630 - 269 - - Antitoxin
- 2220489..2220592 + 104 - - Toxin
NQZ80_RS10655 2220727..2221383 + 657 WP_001559255.1 protein-serine/threonine phosphatase -
NQZ80_RS10660 2221384..2221575 - 192 WP_001296140.1 YebW family protein -
NQZ80_RS10665 2221680..2221916 - 237 WP_001295499.1 YebV family protein -
NQZ80_RS10670 2222034..2223473 - 1440 WP_024186572.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2196576..2223479 26903


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T253359 NZ_CP102244:2220489-2220592 [Escherichia coli O7:H15]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT253359 NZ_CP102244:c2220630-2220362 [Escherichia coli O7:H15]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References