253328

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010166..2010311 Replicon chromosome
Accession NZ_CP102192
Organism Klebsiella pneumoniae strain S270v

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010202..2010304 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010166..2010311 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ65_RS09855 (NQZ65_09860) 2005296..2007356 + 2061 WP_004151449.1 oligopeptidase B -
NQZ65_RS09860 (NQZ65_09865) 2007360..2008019 - 660 WP_002911407.1 exodeoxyribonuclease X -
NQZ65_RS09865 (NQZ65_09870) 2008098..2008328 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NQZ65_RS09870 (NQZ65_09875) 2008441..2008815 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NQZ65_RS09875 (NQZ65_09880) 2008819..2009688 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NQZ65_RS09880 (NQZ65_09885) 2009705..2010043 + 339 WP_002911404.1 YebY family protein -
- 2010166..2010311 - 146 - - Antitoxin
- 2010202..2010304 + 103 - - Toxin
NQZ65_RS09885 (NQZ65_09890) 2010679..2010822 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NQZ65_RS09890 (NQZ65_09895) 2010927..2011895 - 969 WP_004151446.1 VirK/YbjX family protein -
NQZ65_RS09895 (NQZ65_09900) 2012052..2012705 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NQZ65_RS09900 (NQZ65_09905) 2012702..2012893 - 192 WP_002911395.1 YebW family protein -
NQZ65_RS09905 (NQZ65_09910) 2012991..2013230 - 240 WP_002911393.1 YebV family protein -
NQZ65_RS09910 (NQZ65_09915) 2013346..2014779 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253328 NZ_CP102192:2010202-2010304 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253328 NZ_CP102192:c2010311-2010166 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References