Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4766120..4766714 Replicon chromosome
Accession NZ_CP102179
Organism Pseudomonas canavaninivorans strain B21-020

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY40_RS21270 Protein ID WP_258648095.1
Coordinates 4766120..4766422 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag LOY40_RS21275 Protein ID WP_188252113.1
Coordinates 4766415..4766714 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY40_RS21240 (LOY40_21240) 4762006..4762194 + 189 WP_018607615.1 hypothetical protein -
LOY40_RS21245 (LOY40_21245) 4762392..4763102 + 711 WP_258648091.1 TorF family putative porin -
LOY40_RS21250 (LOY40_21250) 4763184..4764050 + 867 WP_258648092.1 DUF6279 family lipoprotein -
LOY40_RS21255 (LOY40_21255) 4764175..4764567 - 393 WP_030141150.1 hypothetical protein -
LOY40_RS21260 (LOY40_21260) 4764756..4765487 + 732 WP_258648093.1 thioredoxin family protein -
LOY40_RS21265 (LOY40_21265) 4765730..4766002 + 273 WP_258648094.1 hypothetical protein -
LOY40_RS21270 (LOY40_21270) 4766120..4766422 + 303 WP_258648095.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY40_RS21275 (LOY40_21275) 4766415..4766714 + 300 WP_188252113.1 putative addiction module antidote protein Antitoxin
LOY40_RS21280 (LOY40_21280) 4766884..4767585 - 702 WP_258648096.1 transposase -
LOY40_RS21285 (LOY40_21285) 4767791..4768183 - 393 WP_181286765.1 hypothetical protein -
LOY40_RS21290 (LOY40_21290) 4768186..4770703 - 2518 Protein_4199 DUF637 domain-containing protein -
LOY40_RS21295 (LOY40_21295) 4771302..4771574 + 273 WP_258648097.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11342.98 Da        Isoelectric Point: 10.0627

>T253290 WP_258648095.1 NZ_CP102179:4766120-4766422 [Pseudomonas canavaninivorans]
MKKIESSKFRSWLKKLKDDTGRARITSRINRLIEGLPGDVAPVGHGLSELRIHYGPGYRVYFYQQGDVLVILLCGGDKGS
QSRDIETAHQIMQAWRAQND

Download         Length: 303 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10772.18 Da        Isoelectric Point: 4.8255

>AT253290 WP_188252113.1 NZ_CP102179:4766415-4766714 [Pseudomonas canavaninivorans]
MTETFTEFDPAEYLSTPEAIAEFMSDALETGDASYIAKAMGVVARAKGMTELARETGLSREQLYRSFSEHGNPTLKTLLA
VMKALGVDMTARPHTHTAS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References