Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4196249..4196796 Replicon chromosome
Accession NZ_CP102179
Organism Pseudomonas canavaninivorans strain B21-020

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOY40_RS18745 Protein ID WP_198796045.1
Coordinates 4196521..4196796 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8RKA9
Locus tag LOY40_RS18740 Protein ID WP_030141313.1
Coordinates 4196249..4196521 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY40_RS18730 (LOY40_18730) 4192991..4194523 + 1533 WP_030141315.1 NADH-quinone oxidoreductase subunit M -
LOY40_RS18735 (LOY40_18735) 4194531..4195994 + 1464 WP_258647916.1 NADH-quinone oxidoreductase subunit NuoN -
LOY40_RS18740 (LOY40_18740) 4196249..4196521 + 273 WP_030141313.1 ribbon-helix-helix domain-containing protein Antitoxin
LOY40_RS18745 (LOY40_18745) 4196521..4196796 + 276 WP_198796045.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY40_RS18750 (LOY40_18750) 4196860..4197969 + 1110 WP_258647917.1 NAD(P)/FAD-dependent oxidoreductase -
LOY40_RS18755 (LOY40_18755) 4198168..4198644 + 477 WP_030141310.1 hemerythrin domain-containing protein -
LOY40_RS18760 (LOY40_18760) 4198697..4199575 - 879 WP_258647918.1 LysR family transcriptional regulator -
LOY40_RS18765 (LOY40_18765) 4199823..4200452 - 630 WP_030141308.1 isochorismate family cysteine hydrolase YcaC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10658.21 Da        Isoelectric Point: 8.5042

>T253288 WP_198796045.1 NZ_CP102179:4196521-4196796 [Pseudomonas canavaninivorans]
MELKWTSKALSDIARLYEFLASVNQPAAARTVQQLTAAPSSLLVNPRIGERLEEFEPRDVRRIQVGHYEMRYEIVGSTLY
LLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10094.38 Da        Isoelectric Point: 6.0723

>AT253288 WP_030141313.1 NZ_CP102179:4196249-4196521 [Pseudomonas canavaninivorans]
MTTTAKTRSVTAHVPVHLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTHEALADVDAGRVIDHQAVQAWADSL
STDAPLPVPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8RKA9

References