Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 526476..527065 Replicon chromosome
Accession NZ_CP102179
Organism Pseudomonas canavaninivorans strain B21-020

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY40_RS02340 Protein ID WP_030140979.1
Coordinates 526476..526781 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY40_RS02345 Protein ID WP_030140978.1
Coordinates 526778..527065 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY40_RS02325 (LOY40_02325) 522990..524057 + 1068 WP_030140982.1 uroporphyrinogen decarboxylase -
LOY40_RS02330 (LOY40_02330) 524106..525380 - 1275 WP_217861077.1 MFS transporter -
LOY40_RS02335 (LOY40_02335) 525500..526417 + 918 WP_030140980.1 LysR family transcriptional regulator -
LOY40_RS02340 (LOY40_02340) 526476..526781 + 306 WP_030140979.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY40_RS02345 (LOY40_02345) 526778..527065 + 288 WP_030140978.1 putative addiction module antidote protein Antitoxin
LOY40_RS02350 (LOY40_02350) 527167..527529 - 363 WP_258648749.1 alpha/beta hydrolase -
LOY40_RS02355 (LOY40_02355) 527519..528148 - 630 WP_258648750.1 alpha/beta hydrolase -
LOY40_RS02360 (LOY40_02360) 528538..529056 + 519 WP_217861079.1 hypothetical protein -
LOY40_RS02365 (LOY40_02365) 529141..529392 - 252 WP_030140975.1 hypothetical protein -
LOY40_RS02370 (LOY40_02370) 529419..529664 - 246 Protein_464 DUF6124 family protein -
LOY40_RS02375 (LOY40_02375) 530108..530707 + 600 WP_258648751.1 helix-turn-helix transcriptional regulator -
LOY40_RS02380 (LOY40_02380) 530697..531575 + 879 WP_258648752.1 queuosine precursor transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11390.06 Da        Isoelectric Point: 10.2763

>T253286 WP_030140979.1 NZ_CP102179:526476-526781 [Pseudomonas canavaninivorans]
MTEIIRSSTFSGWLSKLADSRARMRIQVRVDRMADGNLGDVKALGEGLSEARIDYGPGYRIYFMQQGRQLIILLCGGDKS
SQARDIKQARLIAKSWQEQNP

Download         Length: 306 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10385.72 Da        Isoelectric Point: 4.6286

>AT253286 WP_030140978.1 NZ_CP102179:526778-527065 [Pseudomonas canavaninivorans]
MTEQFTRWDSAEYLKTEEDMANYLDACMDEAGDDPAFIAKALGTIARARGMTQVARDAGLSRENLYRALSGEGNPEFGTI
LKVVKALGLKLHAST

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References