Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 402690..403336 Replicon chromosome
Accession NZ_CP102179
Organism Pseudomonas canavaninivorans strain B21-020

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LOY40_RS01800 Protein ID WP_249876528.1
Coordinates 402690..403106 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LOY40_RS01805 Protein ID WP_030141493.1
Coordinates 403106..403336 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY40_RS01775 (LOY40_01775) 398116..399345 - 1230 WP_258648723.1 SAM-dependent methyltransferase -
LOY40_RS01780 (LOY40_01780) 399326..400015 - 690 WP_030141498.1 ABC transporter permease -
LOY40_RS01785 (LOY40_01785) 400012..400707 - 696 WP_198797081.1 ABC transporter permease -
LOY40_RS01790 (LOY40_01790) 400787..401542 - 756 WP_030141496.1 ABC transporter substrate-binding protein -
LOY40_RS01795 (LOY40_01795) 401556..402329 - 774 WP_030141495.1 ABC transporter ATP-binding protein -
LOY40_RS01800 (LOY40_01800) 402690..403106 - 417 WP_249876528.1 tRNA(fMet)-specific endonuclease VapC Toxin
LOY40_RS01805 (LOY40_01805) 403106..403336 - 231 WP_030141493.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LOY40_RS01810 (LOY40_01810) 403512..403961 + 450 WP_258648724.1 carboxypeptidase regulatory-like domain-containing protein -
LOY40_RS01815 (LOY40_01815) 403971..404417 - 447 WP_030141491.1 hypothetical protein -
LOY40_RS01820 (LOY40_01820) 404458..406692 - 2235 WP_258648725.1 ATP-binding protein -
LOY40_RS01825 (LOY40_01825) 406689..407294 - 606 WP_258648726.1 biliverdin-producing heme oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 390007..403336 13329


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-35)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15305.06 Da        Isoelectric Point: 8.2836

>T253285 WP_249876528.1 NZ_CP102179:c403106-402690 [Pseudomonas canavaninivorans]
MIKFMLDTNICIFTIKNKPQVVREAFIRHHGQLCISAVTLMELIYGAEKSSAPEKNLSVIEGFCARLEVLPFGYDAAAHT
GMIRAELAKIGKPIGPYDQMIAGHARSLGLIVVTNNLKEFERVPGLRVEDWTPLALKP

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8489.49 Da        Isoelectric Point: 4.3719

>AT253285 WP_030141493.1 NZ_CP102179:c403336-403106 [Pseudomonas canavaninivorans]
MEQTTIFMSNRSQAVRLPKAVAMPSDVKRVDVVAIGRARIITPAGEAWDSWFDGDSATADFMAEREQPADQERESF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References