Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2841507..2842054 Replicon chromosome
Accession NZ_CP102176
Organism Pseudomonas mediterranea strain B21-060

Toxin (Protein)


Gene name relE Uniprot ID A0A6I6QH28
Locus tag LOY71_RS12470 Protein ID WP_047698598.1
Coordinates 2841779..2842054 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY71_RS12465 Protein ID WP_265086672.1
Coordinates 2841507..2841779 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY71_RS12445 (LOY71_12450) 2837459..2838130 + 672 WP_041022045.1 Bax inhibitor-1/YccA family protein -
LOY71_RS12450 (LOY71_12455) 2838192..2838629 - 438 WP_047698606.1 Lrp/AsnC family transcriptional regulator -
LOY71_RS12455 (LOY71_12460) 2838763..2839656 + 894 WP_265086712.1 DMT family transporter -
LOY71_RS12460 (LOY71_12465) 2839663..2841288 - 1626 WP_265086671.1 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase -
LOY71_RS12465 (LOY71_12470) 2841507..2841779 + 273 WP_265086672.1 ribbon-helix-helix domain-containing protein Antitoxin
LOY71_RS12470 (LOY71_12475) 2841779..2842054 + 276 WP_047698598.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY71_RS12475 (LOY71_12480) 2842275..2843180 - 906 WP_159285624.1 autotransporter outer membrane beta-barrel domain-containing protein -
LOY71_RS12480 (LOY71_12485) 2843480..2845903 - 2424 WP_230164320.1 autotransporter outer membrane beta-barrel domain-containing protein -
LOY71_RS12485 (LOY71_12490) 2846084..2846884 - 801 WP_230164291.1 endonuclease/exonuclease/phosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10715.26 Da        Isoelectric Point: 8.5042

>T253279 WP_047698598.1 NZ_CP102176:2841779-2842054 [Pseudomonas mediterranea]
MELKWTSKALSDLARLYEFLAAVNQPAAARTVQQLTAAPTTLLDNPRIGERLEEFEPRDVRRIQIGHYEMRYEVVSSTLY
LLRLWHTRENR

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10116.46 Da        Isoelectric Point: 5.6994

>AT253279 WP_265086672.1 NZ_CP102176:2841507-2841779 [Pseudomonas mediterranea]
MATPTKTRSVTAHVPVQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAIQAWADSL
STDTPLPVPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6I6QH28

Antitoxin

Source ID Structure

References