Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 488096..488685 Replicon chromosome
Accession NZ_CP102176
Organism Pseudomonas mediterranea strain B21-060

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LOY71_RS02145 Protein ID WP_081993227.1
Coordinates 488096..488401 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOY71_RS02150 Protein ID WP_047700469.1
Coordinates 488398..488685 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY71_RS02120 (LOY71_02120) 483185..484030 + 846 WP_159284831.1 type II secretion system protein GspK -
LOY71_RS02125 (LOY71_02125) 484030..485133 + 1104 WP_265086426.1 type II secretion system protein GspL -
LOY71_RS02130 (LOY71_02130) 485133..485588 + 456 WP_055127146.1 type II secretion system protein GspM -
LOY71_RS02135 (LOY71_02135) 485741..487018 - 1278 WP_047700472.1 MFS transporter -
LOY71_RS02140 (LOY71_02140) 487138..488073 + 936 WP_047700471.1 LysR family transcriptional regulator -
LOY71_RS02145 (LOY71_02145) 488096..488401 + 306 WP_081993227.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOY71_RS02150 (LOY71_02150) 488398..488685 + 288 WP_047700469.1 putative addiction module antidote protein Antitoxin
LOY71_RS02155 (LOY71_02155) 488733..492749 - 4017 WP_265086427.1 hypothetical protein -
LOY71_RS02160 (LOY71_02160) 493060..493506 - 447 WP_047700467.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11432.14 Da        Isoelectric Point: 10.0053

>T253277 WP_081993227.1 NZ_CP102176:488096-488401 [Pseudomonas mediterranea]
MTEIIRSCTFSGWLSKLADSRARIRIQVRIDRMADGNLGDVKAIGEGLSEARIDYGPGYRIYFMQQGRQLIILLCGGDKS
SQTRDIKQARLIAKSWQEQNP

Download         Length: 306 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10413.73 Da        Isoelectric Point: 4.6412

>AT253277 WP_047700469.1 NZ_CP102176:488398-488685 [Pseudomonas mediterranea]
MTEQFTRWDSAEYLKTEEDMANYLDACMEEAGDDPAFIAKALGTIARARGMSQVARDAGLSRENLYRALSGEGNPEFGTI
LKVVRALGLKLHAST

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References