Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1358644..1359127 Replicon chromosome
Accession NZ_CP102149
Organism Streptococcus suis strain DNC13

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NQZ89_RS07060 Protein ID WP_257103993.1
Coordinates 1358867..1359127 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NQZ89_RS07055 Protein ID WP_172009559.1
Coordinates 1358644..1358865 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ89_RS07030 (NQZ89_07030) 1353945..1355183 + 1239 WP_257103989.1 DNA recombination protein RmuC -
NQZ89_RS07035 (NQZ89_07035) 1355173..1356117 + 945 WP_257103990.1 3'-5' exoribonuclease YhaM family protein -
NQZ89_RS07040 (NQZ89_07040) 1356120..1356998 + 879 WP_257103991.1 phosphotransferase -
NQZ89_RS07045 (NQZ89_07045) 1357090..1357908 + 819 WP_105111720.1 pur operon repressor -
NQZ89_RS07050 (NQZ89_07050) 1358029..1358364 - 336 WP_257103992.1 thiol reductase thioredoxin -
NQZ89_RS07055 (NQZ89_07055) 1358644..1358865 + 222 WP_172009559.1 DUF6290 family protein Antitoxin
NQZ89_RS07060 (NQZ89_07060) 1358867..1359127 + 261 WP_257103993.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQZ89_RS07065 (NQZ89_07065) 1359307..1359765 + 459 WP_105111716.1 CtsR family transcriptional regulator -
NQZ89_RS07070 (NQZ89_07070) 1359770..1362220 + 2451 WP_257103994.1 ATP-dependent Clp protease ATP-binding subunit -
NQZ89_RS07075 (NQZ89_07075) 1362281..1363318 + 1038 WP_105122239.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10511.98 Da        Isoelectric Point: 9.8746

>T253254 WP_257103993.1 NZ_CP102149:1358867-1359127 [Streptococcus suis]
MYRIDYSKRAQRQIRKMDKQVQRLLFTWIDKHLDGTENPRQHGKGLTDNRANEWGYRIGDYRLIYDIQEDKLVILALEFG
HRKDIY

Download         Length: 261 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8615.58 Da        Isoelectric Point: 4.6104

>AT253254 WP_172009559.1 NZ_CP102149:1358644-1358865 [Streptococcus suis]
MSTVTVRLNQEEETFFKSYAQLTGQSLSSLFKKALERTIEDEFDLKIYHQAYKEYQDDPETISHADFKKELGF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References