Detailed information of TA system TA253250

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): abiEi-abiEii/AbiEii-AbiEi
• Location: 14631..16063
• Replicon: chromosome
• Accession: NZ_CP102149
• Organism: Streptococcus suis strain DNC13

Toxin (Protein)

• Gene name: abiEi
• Uniprot ID: -
• Locus tag: NQZ89_RS00080
• Protein ID: WP_257104486.1
• Coordinates: 14631..15476 (-)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: abiEii
• Uniprot ID: -
• Locus tag: NQZ89_RS00085
• Protein ID: WP_257104487.1
• Coordinates: 15473..16063 (-)
• Length: 197 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NQZ89_RS00065 (NQZ89_00065)	10198..12999	+	2802	WP_257104484.1	phage tail tip lysozyme	-
NQZ89_RS00070 (NQZ89_00070)	13137..14147	+	1011	WP_257104485.1	Abi family protein	-
NQZ89_RS00075 (NQZ89_00075)	14261..14545	+	285	Protein_14	CHAP domain-containing protein	-
NQZ89_RS00080 (NQZ89_00080)	14631..15476	-	846	WP_257104486.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
NQZ89_RS00085 (NQZ89_00085)	15473..16063	-	591	WP_257104487.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (33-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-50)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 32394.95 Da
• Isoelectric Point: 4.8302

>T253250 WP_257104486.1 NZ_CP102149:c15476-14631 [Streptococcus suis]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEE
TVKQQLEEVLADSDEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLRNACQRTFSYRETELDFVKIIELLERFKSDP
IQNKQWQNYSKKYSYTKGISLADVLDEMISLITIIISTDSD

Nucleotide

• Length: 846 bp

Antitoxin

Protein

• Length: 197 a.a.
• Molecular weight: 23046.57 Da
• Isoelectric Point: 7.8056

>AT253250 WP_257104487.1 NZ_CP102149:c16063-15473 [Streptococcus suis]
MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFRVEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYL
QQFTDEIPQYFDVTVPRGYRFNTPPANLNIHFVSKEYSELGMTTVPTPMGNNVRVYDFERVICDFVIHREKIDSELFVKT
LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLV

Nucleotide

• Length: 591 bp