Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1892493..1893108 Replicon chromosome
Accession NZ_CP102148
Organism Streptococcus suis strain DNC15

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NQZ90_RS09210 Protein ID WP_161496224.1
Coordinates 1892493..1892828 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A075SJ65
Locus tag NQZ90_RS09215 Protein ID WP_024381089.1
Coordinates 1892821..1893108 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ90_RS09190 (NQZ90_09190) 1888384..1888569 - 186 WP_009910840.1 hypothetical protein -
NQZ90_RS09195 (NQZ90_09195) 1888563..1889336 - 774 WP_105141534.1 nucleoside phosphorylase -
NQZ90_RS09200 (NQZ90_09200) 1889351..1889968 - 618 WP_105141533.1 serine O-acetyltransferase -
NQZ90_RS09205 (NQZ90_09205) 1890022..1892241 - 2220 WP_105141532.1 polyribonucleotide nucleotidyltransferase -
NQZ90_RS09210 (NQZ90_09210) 1892493..1892828 - 336 WP_161496224.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQZ90_RS09215 (NQZ90_09215) 1892821..1893108 - 288 WP_024381089.1 XRE family transcriptional regulator Antitoxin
NQZ90_RS09220 (NQZ90_09220) 1893515..1893784 - 270 WP_002938849.1 30S ribosomal protein S15 -
NQZ90_RS09225 (NQZ90_09225) 1893987..1895264 - 1278 WP_024407945.1 solute carrier family 23 protein -
NQZ90_RS09230 (NQZ90_09230) 1895518..1897413 - 1896 WP_044673271.1 DUF262 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12783.86 Da        Isoelectric Point: 9.5189

>T253248 WP_161496224.1 NZ_CP102148:c1892828-1892493 [Streptococcus suis]
MDKYQVNLPLAIYEELAAIRSYIREELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGPLVPGHLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10686.33 Da        Isoelectric Point: 4.2626

>AT253248 WP_024381089.1 NZ_CP102148:c1893108-1892821 [Streptococcus suis]
MALTAEKKLINFQSEKSLVEEAKEVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFAELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A075SJ65

References