Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sezT-pezT/zeta-HTH_XRE
Location 1338287..1339539 Replicon chromosome
Accession NZ_CP102145
Organism Streptococcus suis strain DNS20

Toxin (Protein)


Gene name sezT Uniprot ID -
Locus tag NQZ91_RS06610 Protein ID WP_257117183.1
Coordinates 1338287..1339063 (-) Length 259 a.a.

Antitoxin (Protein)


Gene name pezT Uniprot ID -
Locus tag NQZ91_RS06615 Protein ID WP_257117185.1
Coordinates 1339063..1339539 (-) Length 159 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ91_RS06585 (NQZ91_06585) 1334147..1335124 - 978 WP_257117179.1 tagatose-bisphosphate aldolase -
NQZ91_RS06590 (NQZ91_06590) 1335126..1336058 - 933 WP_257117180.1 tagatose-6-phosphate kinase -
NQZ91_RS06595 (NQZ91_06595) 1336068..1336583 - 516 WP_002941130.1 galactose-6-phosphate isomerase subunit LacB -
NQZ91_RS06600 (NQZ91_06600) 1336610..1337032 - 423 WP_024384734.1 galactose-6-phosphate isomerase subunit LacA -
NQZ91_RS06605 (NQZ91_06605) 1337239..1338006 - 768 WP_257117182.1 DeoR/GlpR family DNA-binding transcription regulator -
NQZ91_RS06610 (NQZ91_06610) 1338287..1339063 - 777 WP_257117183.1 type II toxin-antitoxin system toxin PezT Toxin
NQZ91_RS06615 (NQZ91_06615) 1339063..1339539 - 477 WP_257117185.1 type II toxin-antitoxin system antitoxin PezA Antitoxin
NQZ91_RS06620 (NQZ91_06620) 1339655..1340851 - 1197 WP_257105021.1 iron-containing alcohol dehydrogenase -
NQZ91_RS06625 (NQZ91_06625) 1340989..1341579 - 591 WP_105111096.1 CHAP domain-containing protein -
NQZ91_RS06630 (NQZ91_06630) 1341798..1342562 + 765 WP_257103943.1 alpha/beta hydrolase -
NQZ91_RS06635 (NQZ91_06635) 1342666..1343817 + 1152 WP_105111097.1 glycerophosphodiester phosphodiesterase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(28-215)

Antitoxin

Cro/C1-type helix-turn-helix domain

(3-60)


Sequences

Toxin        


Download         Length: 259 a.a.        Molecular weight: 29589.36 Da        Isoelectric Point: 5.9856

>T253245 WP_257117183.1 NZ_CP102145:c1339063-1338287 [Streptococcus suis]
MRLEEFSEAEFQKALQRTIRALTRGKTIPNQPRAIFLGGQSGAGKTTIHRIKQKEFQGNIIIIDGDSYRSQHPDYLALQD
KYGKDSVDYTKEFAGKMVEHLVDELSTQGYHLLIEGTLRTTQVPRQTAQLLSSKGYQVSLAVIGTKPELSYLSTLIRYEE
LYAIDPNQARATPKEHHDGIVENLVDNLRELESEKFFDQIQIYQRDRTCIYDSKTDKDSAAEVLQECLFGKWSKVEEEMM
KFGQERLREMSKSNGNDV

Download         Length: 777 bp

Antitoxin


Download         Length: 159 a.a.        Molecular weight: 18286.71 Da        Isoelectric Point: 4.4042

>AT253245 WP_257117185.1 NZ_CP102145:c1339539-1339063 [Streptococcus suis]
MIGENIKSLRQTHDLTQPEFAKMVGISRNSLSRYENGTSKVSTELIDRICQKFNVSYVDIVGEDKMLTPVEDYQLTLKVE
VIKERGAAILSQLYRYQDSQDIAFDDESNPWILMSDDLAELINTKIYLVDTFDEIERYNGYLDGIERMLDMVHHRVVA

Download         Length: 477 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References