253243

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1271034..1271517 Replicon chromosome
Accession NZ_CP102145
Organism Streptococcus suis strain DNS20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NQZ91_RS06230 Protein ID WP_257103993.1
Coordinates 1271034..1271294 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NQZ91_RS06235 Protein ID WP_172009559.1
Coordinates 1271296..1271517 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ91_RS06215 (NQZ91_06215) 1266843..1267880 - 1038 WP_257117149.1 AAA family ATPase -
NQZ91_RS06220 (NQZ91_06220) 1267941..1270391 - 2451 WP_105111715.1 ATP-dependent Clp protease ATP-binding subunit -
NQZ91_RS06225 (NQZ91_06225) 1270396..1270854 - 459 WP_105111716.1 CtsR family transcriptional regulator -
NQZ91_RS06230 (NQZ91_06230) 1271034..1271294 - 261 WP_257103993.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQZ91_RS06235 (NQZ91_06235) 1271296..1271517 - 222 WP_172009559.1 DUF6290 family protein Antitoxin
NQZ91_RS06240 (NQZ91_06240) 1271797..1272132 + 336 WP_257103992.1 thiol reductase thioredoxin -
NQZ91_RS06245 (NQZ91_06245) 1272253..1273071 - 819 WP_105111720.1 pur operon repressor -
NQZ91_RS06250 (NQZ91_06250) 1273163..1274047 - 885 WP_257117150.1 phosphotransferase -
NQZ91_RS06255 (NQZ91_06255) 1274044..1274988 - 945 WP_257103990.1 3'-5' exoribonuclease YhaM family protein -
NQZ91_RS06260 (NQZ91_06260) 1274978..1276216 - 1239 WP_257103989.1 DNA recombination protein RmuC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10511.98 Da        Isoelectric Point: 9.8746

>T253243 WP_257103993.1 NZ_CP102145:c1271294-1271034 [Streptococcus suis]
MYRIDYSKRAQRQIRKMDKQVQRLLFTWIDKHLDGTENPRQHGKGLTDNRANEWGYRIGDYRLIYDIQEDKLVILALEFG
HRKDIY

Download         Length: 261 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8615.58 Da        Isoelectric Point: 4.6104

>AT253243 WP_172009559.1 NZ_CP102145:c1271517-1271296 [Streptococcus suis]
MSTVTVRLNQEEETFFKSYAQLTGQSLSSLFKKALERTIEDEFDLKIYHQAYKEYQDDPETISHADFKKELGF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References