253242

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1189251..1189809 Replicon chromosome
Accession NZ_CP102145
Organism Streptococcus suis strain DNS20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NQZ91_RS05865 Protein ID WP_257117111.1
Coordinates 1189528..1189809 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NQZ91_RS05860 Protein ID WP_257118048.1
Coordinates 1189251..1189538 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ91_RS05840 (NQZ91_05840) 1184707..1185198 + 492 WP_105110693.1 phosphatidylglycerophosphatase A -
NQZ91_RS05845 (NQZ91_05845) 1185243..1187702 - 2460 WP_257117109.1 YhgE/Pip domain-containing protein -
NQZ91_RS05850 (NQZ91_05850) 1187828..1188367 + 540 WP_105122128.1 TetR-like C-terminal domain-containing protein -
NQZ91_RS05855 (NQZ91_05855) 1188395..1189225 - 831 WP_257117110.1 Cof-type HAD-IIB family hydrolase -
NQZ91_RS05860 (NQZ91_05860) 1189251..1189538 + 288 WP_257118048.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NQZ91_RS05865 (NQZ91_05865) 1189528..1189809 + 282 WP_257117111.1 type II toxin-antitoxin system YafQ family toxin Toxin
NQZ91_RS05870 (NQZ91_05870) 1189861..1190205 - 345 WP_172060038.1 hypothetical protein -
NQZ91_RS05875 (NQZ91_05875) 1190365..1191591 - 1227 WP_257118049.1 CapA family protein -
NQZ91_RS05880 (NQZ91_05880) 1191831..1193018 + 1188 WP_257117112.1 chromate transporter -
NQZ91_RS05885 (NQZ91_05885) 1193116..1193328 + 213 WP_172079308.1 hypothetical protein -
NQZ91_RS05890 (NQZ91_05890) 1193368..1194312 - 945 WP_172079307.1 dihydroorotate oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10862.53 Da        Isoelectric Point: 6.6375

>T253242 WP_257117111.1 NZ_CP102145:1189528-1189809 [Streptococcus suis]
MKNNISNKVHEQIQKSYKLMKKRGYDLGLLEEIITKLSQGIPLEDKHQNHMLTGNFSGYYECHIKPDWLLIYLIENDILT
LTLIDTGTHSDLF

Download         Length: 282 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10713.11 Da        Isoelectric Point: 4.6282

>AT253242 WP_257118048.1 NZ_CP102145:1189251-1189538 [Streptococcus suis]
ISNQRPTSPTQIRIETTVKEDANALFARLGLDMSSAENIFLRQCVLRGGLPFSVELPKYNQETLEAMEEARKISRNPNVP
SYATVQDLFKALDEE

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References