253241

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 419973..420448 Replicon chromosome
Accession NZ_CP102145
Organism Streptococcus suis strain DNS20

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NQZ91_RS02045 Protein ID WP_172067485.1
Coordinates 419973..420236 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NQZ91_RS02050 Protein ID WP_172067487.1
Coordinates 420233..420448 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ91_RS02025 (NQZ91_02025) 415131..417086 - 1956 WP_257117744.1 fructose-specific PTS transporter subunit EIIC -
NQZ91_RS02030 (NQZ91_02030) 417083..417994 - 912 WP_257117745.1 1-phosphofructokinase -
NQZ91_RS02035 (NQZ91_02035) 417991..418734 - 744 WP_257117746.1 DeoR/GlpR family DNA-binding transcription regulator -
NQZ91_RS02040 (NQZ91_02040) 418844..419905 - 1062 WP_172074744.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
NQZ91_RS02045 (NQZ91_02045) 419973..420236 - 264 WP_172067485.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQZ91_RS02050 (NQZ91_02050) 420233..420448 - 216 WP_172067487.1 DUF6290 family protein Antitoxin
NQZ91_RS02055 (NQZ91_02055) 420641..420778 - 138 WP_257104465.1 hypothetical protein -
NQZ91_RS02060 (NQZ91_02060) 420818..421766 - 949 Protein_406 IS30 family transposase -
NQZ91_RS02065 (NQZ91_02065) 421972..422994 - 1023 WP_105160953.1 branched-chain amino acid aminotransferase -
NQZ91_RS02070 (NQZ91_02070) 423222..423950 - 729 WP_105123272.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
NQZ91_RS02075 (NQZ91_02075) 423940..424458 - 519 WP_257117747.1 ribosome maturation factor RimM -
NQZ91_RS02080 (NQZ91_02080) 424681..424923 - 243 WP_257117748.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 420929..421267 338


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10300.83 Da        Isoelectric Point: 10.7218

>T253241 WP_172067485.1 NZ_CP102145:c420236-419973 [Streptococcus suis]
MSYKVRLTPKANKQLRKLDAYTRNTILTWIKKNLYQTDNPRLHGKGLTANRSGAWRYRVGNYRILANIYDDEIVIEVFAI
GHRRDSY

Download         Length: 264 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8276.41 Da        Isoelectric Point: 4.0414

>AT253241 WP_172067487.1 NZ_CP102145:c420448-420233 [Streptococcus suis]
MTTMTLRINDEDSKLIKNYIQLHGLTISEFARQAMLERIEDEYDLAVLRQAMAEDDGVRIPIEDLFEEFGI

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References