Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1929209..1929824 Replicon chromosome
Accession NZ_CP102141
Organism Streptococcus suis strain DNR48

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NQZ93_RS09560 Protein ID WP_024389183.1
Coordinates 1929209..1929544 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A075SJ65
Locus tag NQZ93_RS09565 Protein ID WP_024381089.1
Coordinates 1929537..1929824 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ93_RS09540 (NQZ93_09540) 1925100..1925285 - 186 WP_009910840.1 hypothetical protein -
NQZ93_RS09545 (NQZ93_09545) 1925279..1926052 - 774 WP_024381086.1 nucleoside phosphorylase -
NQZ93_RS09550 (NQZ93_09550) 1926067..1926684 - 618 WP_015647409.1 serine O-acetyltransferase -
NQZ93_RS09555 (NQZ93_09555) 1926738..1928957 - 2220 WP_024381087.1 polyribonucleotide nucleotidyltransferase -
NQZ93_RS09560 (NQZ93_09560) 1929209..1929544 - 336 WP_024389183.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQZ93_RS09565 (NQZ93_09565) 1929537..1929824 - 288 WP_024381089.1 XRE family transcriptional regulator Antitoxin
NQZ93_RS09570 (NQZ93_09570) 1930138..1930407 - 270 WP_002938849.1 30S ribosomal protein S15 -
NQZ93_RS09575 (NQZ93_09575) 1930662..1931303 - 642 WP_002938850.1 ABC transporter ATP-binding protein -
NQZ93_RS09580 (NQZ93_09580) 1931296..1932042 - 747 WP_225533344.1 hypothetical protein -
NQZ93_RS09585 (NQZ93_09585) 1932791..1933555 - 765 WP_002938853.1 hypothetical protein -
NQZ93_RS09590 (NQZ93_09590) 1933640..1934050 - 411 WP_013730575.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12818.86 Da        Isoelectric Point: 9.1835

>T253228 WP_024389183.1 NZ_CP102141:c1929544-1929209 [Streptococcus suis]
MDKYQVNLPLAIYEELADIRSYIREELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGPLVPGQLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10686.33 Da        Isoelectric Point: 4.2626

>AT253228 WP_024381089.1 NZ_CP102141:c1929824-1929537 [Streptococcus suis]
MALTAEKKLINFQSEKSLVEEAKEVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFAELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A075SJ65

References