Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1929209..1929824 Replicon chromosome
Accession NZ_CP102141
Organism Streptococcus suis strain DNR48

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NQZ93_RS09560 Protein ID WP_024389183.1
Coordinates 1929209..1929544 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A075SJ65
Locus tag NQZ93_RS09565 Protein ID WP_024381089.1
Coordinates 1929537..1929824 (-) Length 96 a.a.

Genomic Context

NQZ93_RS09540NQZ93_RS09545NQZ93_RS09550NQZ93_RS09555NQZ93_RS09560NQZ93_RS09565NQZ93_RS09570NQZ93_RS09575NQZ93_RS09580NQZ93_RS09585NQZ93_RS09590
Location: 1925100..1925285 (186 bp)
Type: Others
Protein ID: WP_009910840.1
Location: 1925279..1926052 (774 bp)
Type: Others
Protein ID: WP_024381086.1
Location: 1926067..1926684 (618 bp)
Type: Others
Protein ID: WP_015647409.1
Location: 1926738..1928957 (2220 bp)
Type: Others
Protein ID: WP_024381087.1
Location: 1929209..1929544 (336 bp)
Type: Toxin
Protein ID: WP_024389183.1
Location: 1929537..1929824 (288 bp)
Type: Antitoxin
Protein ID: WP_024381089.1
Location: 1930138..1930407 (270 bp)
Type: Others
Protein ID: WP_002938849.1
Location: 1930662..1931303 (642 bp)
Type: Others
Protein ID: WP_002938850.1
Location: 1931296..1932042 (747 bp)
Type: Others
Protein ID: WP_225533344.1
Location: 1932791..1933555 (765 bp)
Type: Others
Protein ID: WP_002938853.1
Location: 1933640..1934050 (411 bp)
Type: Others
Protein ID: WP_013730575.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NQZ93_RS09540 (NQZ93_09540)1925100..1925285-186WP_009910840.1hypothetical protein-
NQZ93_RS09545 (NQZ93_09545)1925279..1926052-774WP_024381086.1nucleoside phosphorylase-
NQZ93_RS09550 (NQZ93_09550)1926067..1926684-618WP_015647409.1serine O-acetyltransferase-
NQZ93_RS09555 (NQZ93_09555)1926738..1928957-2220WP_024381087.1polyribonucleotide nucleotidyltransferase-
NQZ93_RS09560 (NQZ93_09560)1929209..1929544-336WP_024389183.1type II toxin-antitoxin system RelE/ParE family toxinToxin
NQZ93_RS09565 (NQZ93_09565)1929537..1929824-288WP_024381089.1XRE family transcriptional regulatorAntitoxin
NQZ93_RS09570 (NQZ93_09570)1930138..1930407-270WP_002938849.130S ribosomal protein S15-
NQZ93_RS09575 (NQZ93_09575)1930662..1931303-642WP_002938850.1ABC transporter ATP-binding protein-
NQZ93_RS09580 (NQZ93_09580)1931296..1932042-747WP_225533344.1hypothetical protein-
NQZ93_RS09585 (NQZ93_09585)1932791..1933555-765WP_002938853.1hypothetical protein-
NQZ93_RS09590 (NQZ93_09590)1933640..1934050-411WP_013730575.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12818.86 Da        Isoelectric Point: 9.1835

>T253228 WP_024389183.1 NZ_CP102141:c1929544-1929209 [Streptococcus suis]
MDKYQVNLPLAIYEELADIRSYIREELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGPLVPGQLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10686.33 Da        Isoelectric Point: 4.2626

>AT253228 WP_024381089.1 NZ_CP102141:c1929824-1929537 [Streptococcus suis]
MALTAEKKLINFQSEKSLVEEAKEVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFAELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A075SJ65

References