Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 3090223..3091937 | Replicon | chromosome |
| Accession | NZ_CP102108 | ||
| Organism | Aeromonas veronii strain GD21SC2322TT | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | - |
| Locus tag | NQU90_RS14140 | Protein ID | WP_257123376.1 |
| Coordinates | 3091284..3091937 (-) | Length | 218 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | A0A6I4WU85 |
| Locus tag | NQU90_RS14135 | Protein ID | WP_041206015.1 |
| Coordinates | 3090223..3091287 (-) | Length | 355 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NQU90_RS14120 (NQU90_14120) | 3085347..3086285 | + | 939 | WP_257123374.1 | restriction endonuclease | - |
| NQU90_RS14125 (NQU90_14125) | 3086304..3087017 | - | 714 | WP_005331303.1 | SprT family zinc-dependent metalloprotease | - |
| NQU90_RS14130 (NQU90_14130) | 3087017..3090148 | - | 3132 | WP_257123375.1 | HsdR family type I site-specific deoxyribonuclease | - |
| NQU90_RS14135 (NQU90_14135) | 3090223..3091287 | - | 1065 | WP_041206015.1 | macro domain-containing protein | Antitoxin |
| NQU90_RS14140 (NQU90_14140) | 3091284..3091937 | - | 654 | WP_257123376.1 | DUF4433 domain-containing protein | Toxin |
| NQU90_RS14145 (NQU90_14145) | 3092204..3093514 | - | 1311 | WP_257123377.1 | restriction endonuclease subunit S | - |
| NQU90_RS14150 (NQU90_14150) | 3093514..3095961 | - | 2448 | WP_257123378.1 | type I restriction-modification system subunit M | - |
| NQU90_RS14155 (NQU90_14155) | 3096147..3096593 | - | 447 | WP_021138009.1 | hypothetical protein | - |
| NQU90_RS14160 (NQU90_14160) | 3096740..3096928 | - | 189 | WP_021138010.1 | DUF3283 family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 218 a.a. Molecular weight: 25316.92 Da Isoelectric Point: 7.0173
>T253198 WP_257123376.1 NZ_CP102108:c3091937-3091284 [Aeromonas veronii]
MAYDYSQSLNPQKALIFRIVHRDNLEWILTHGLWAGNGQQQSPHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPQRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLGRIDWPLLQRRDFKRDADDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR
MAYDYSQSLNPQKALIFRIVHRDNLEWILTHGLWAGNGQQQSPHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPQRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLGRIDWPLLQRRDFKRDADDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR
Download Length: 654 bp
Antitoxin
Download Length: 355 a.a. Molecular weight: 39588.70 Da Isoelectric Point: 6.5002
>AT253198 WP_041206015.1 NZ_CP102108:c3091287-3090223 [Aeromonas veronii]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSSQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLQTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSSQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLQTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV
Download Length: 1065 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|