Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1182822..1183461 Replicon chromosome
Accession NZ_CP102099
Organism Acinetobacter colistiniresistens strain C-214

Toxin (Protein)


Gene name cptA Uniprot ID N9PU81
Locus tag NQU59_RS05730 Protein ID WP_005238574.1
Coordinates 1183072..1183461 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N9PKX0
Locus tag NQU59_RS05725 Protein ID WP_005238573.1
Coordinates 1182822..1183079 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQU59_RS05700 (NQU59_05700) 1177972..1178337 + 366 WP_004641032.1 50S ribosomal protein L17 -
NQU59_RS05705 (NQU59_05705) 1178533..1179030 + 498 WP_257065295.1 GNAT family N-acetyltransferase -
NQU59_RS05710 (NQU59_05710) 1179285..1180775 + 1491 WP_005238570.1 NAD(P)/FAD-dependent oxidoreductase -
NQU59_RS05715 (NQU59_05715) 1180902..1181402 + 501 WP_257065296.1 DUF2059 domain-containing protein -
NQU59_RS05720 (NQU59_05720) 1181462..1182634 - 1173 WP_005238572.1 acyl-CoA dehydrogenase family protein -
NQU59_RS05725 (NQU59_05725) 1182822..1183079 + 258 WP_005238573.1 succinate dehydrogenase assembly factor 2 Antitoxin
NQU59_RS05730 (NQU59_05730) 1183072..1183461 + 390 WP_005238574.1 hypothetical protein Toxin
NQU59_RS05735 (NQU59_05735) 1183667..1183876 + 210 WP_005238575.1 hypothetical protein -
NQU59_RS05740 (NQU59_05740) 1184236..1185351 + 1116 WP_005238578.1 hypothetical protein -
NQU59_RS05745 (NQU59_05745) 1185428..1185988 + 561 WP_257065297.1 rhombosortase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15706.77 Da        Isoelectric Point: 10.2879

>T253196 WP_005238574.1 NZ_CP102099:1183072-1183461 [Acinetobacter colistiniresistens]
MAKHVFELQYSRFAFVLQLLLLIFLLSLLYALVSIGWWLLSLLGMTISWFVFLRQPQIRRFEYLDHQDCSFEFSDPTLKI
QRRQIVKILDHQLYIALYFSHKKHKPCIVWWDQLSYAQWKKLKIRAKLS

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10145.55 Da        Isoelectric Point: 4.4698

>AT253196 WP_005238573.1 NZ_CP102099:1182822-1183079 [Acinetobacter colistiniresistens]
MSDEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLTADTAEKALFAELVDQEDPDLLDWFMEVGEPPRTELKDFILKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB N9PU81

Antitoxin

Source ID Structure
AlphaFold DB N9PKX0

References