Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1051810..1052369 Replicon chromosome
Accession NZ_CP102097
Organism Vibrio japonicus strain JCM 31412

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NP165_RS18055 Protein ID WP_257085882.1
Coordinates 1051810..1052088 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0L8TUJ0
Locus tag NP165_RS18060 Protein ID WP_005483196.1
Coordinates 1052085..1052369 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP165_RS18030 (NP165_18030) 1046843..1047796 + 954 WP_257085860.1 IS1595 family transposase -
NP165_RS18035 (NP165_18035) 1047799..1048122 + 324 Protein_951 GNAT family N-acetyltransferase -
NP165_RS18040 (NP165_18040) 1049859..1050317 + 459 WP_257085880.1 GNAT family N-acetyltransferase -
NP165_RS18045 (NP165_18045) 1050477..1050881 + 405 WP_257085873.1 DUF1801 domain-containing protein -
NP165_RS18050 (NP165_18050) 1051031..1051672 + 642 WP_257085881.1 hypothetical protein -
NP165_RS18055 (NP165_18055) 1051810..1052088 - 279 WP_257085882.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NP165_RS18060 (NP165_18060) 1052085..1052369 - 285 WP_005483196.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NP165_RS18065 (NP165_18065) 1052564..1053241 + 678 WP_257085883.1 HNH endonuclease -
NP165_RS18070 (NP165_18070) 1053858..1054838 + 981 WP_069540583.1 hypothetical protein -
NP165_RS18075 (NP165_18075) 1054835..1054951 + 117 WP_254661927.1 DUF3265 domain-containing protein -
NP165_RS18080 (NP165_18080) 1055500..1055934 + 435 WP_257085884.1 GNAT family N-acetyltransferase -
NP165_RS18085 (NP165_18085) 1056074..1056835 + 762 WP_050907847.1 hypothetical protein -
NP165_RS18090 (NP165_18090) 1057019..1057258 - 240 WP_031778212.1 RNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1009525..1078214 68689


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-45)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10935.58 Da        Isoelectric Point: 4.2698

>T253190 WP_257085882.1 NZ_CP102097:c1052088-1051810 [Vibrio japonicus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEEKVENLLEQPLMGVQRDGIRGRLLIIPDISMIVSYWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11083.43 Da        Isoelectric Point: 9.2167

>AT253190 WP_005483196.1 NZ_CP102097:c1052369-1052085 [Vibrio japonicus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFLEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0L8TUJ0

References