Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 1886622..1887237 Replicon chromosome
Accession NZ_CP102094
Organism Streptococcus suis strain 12RC1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NQZ84_RS09195 Protein ID WP_024401942.1
Coordinates 1886622..1886957 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A075SJ65
Locus tag NQZ84_RS09200 Protein ID WP_024381089.1
Coordinates 1886950..1887237 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ84_RS09180 (NQZ84_09180) 1882576..1883436 - 861 WP_044676837.1 GNAT family N-acetyltransferase -
NQZ84_RS09185 (NQZ84_09185) 1883480..1884097 - 618 WP_024400199.1 serine O-acetyltransferase -
NQZ84_RS09190 (NQZ84_09190) 1884151..1886370 - 2220 WP_257047465.1 polyribonucleotide nucleotidyltransferase -
NQZ84_RS09195 (NQZ84_09195) 1886622..1886957 - 336 WP_024401942.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQZ84_RS09200 (NQZ84_09200) 1886950..1887237 - 288 WP_024381089.1 XRE family transcriptional regulator Antitoxin
NQZ84_RS09205 (NQZ84_09205) 1887560..1887829 - 270 WP_002938849.1 30S ribosomal protein S15 -
NQZ84_RS09210 (NQZ84_09210) 1888034..1889311 - 1278 WP_044677860.1 solute carrier family 23 protein -
NQZ84_RS09215 (NQZ84_09215) 1889530..1890003 - 474 WP_024395336.1 hypothetical protein -
NQZ84_RS09220 (NQZ84_09220) 1889984..1890202 - 219 WP_014638668.1 helix-turn-helix transcriptional regulator -
NQZ84_RS09225 (NQZ84_09225) 1890348..1890857 - 510 WP_029171081.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(15-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12700.73 Da        Isoelectric Point: 9.1847

>T253185 WP_024401942.1 NZ_CP102094:c1886957-1886622 [Streptococcus suis]
MDKYQVNLPLAIYEELAGIRSYISEELKSPDAADKKIQELIAGLRSLEIFPERGFNVDERSKKGPLVPGHLTRGLPIKKD
YIAIYNIDEAQKVVNVRYLVASKSDYMRLFK

Download         Length: 336 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10686.33 Da        Isoelectric Point: 4.2626

>AT253185 WP_024381089.1 NZ_CP102094:c1887237-1886950 [Streptococcus suis]
MALTAEKKLINFQSEKSLVEEAKEVLASQNMTMTQALNLFLKNIVVTGEIGLKSEEELEKERLFAELQAEVMKNVAEMNA
GNYLSLDEMETKLFG

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A075SJ65

References