Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 849664..850178 Replicon chromosome
Accession NZ_CP102089
Organism Staphylococcus capitis subsp. capitis strain H17

Toxin (Protein)


Gene name TsdT Uniprot ID A0A1J4E3P3
Locus tag NF392_RS03960 Protein ID WP_023351364.1
Coordinates 849972..850178 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag NF392_RS03955 Protein ID WP_049399286.1
Coordinates 849664..849957 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF392_RS03930 844822..845610 + 789 WP_023351361.1 hydroxyethylthiazole kinase -
NF392_RS03935 845617..846255 + 639 WP_023351362.1 thiamine phosphate synthase -
NF392_RS03940 846344..847216 + 873 WP_002435877.1 membrane protein insertase YidC -
NF392_RS03945 847275..847937 - 663 WP_023351363.1 HD domain-containing protein -
NF392_RS03950 847994..849478 - 1485 WP_002435854.1 cardiolipin synthase -
NF392_RS03955 849664..849957 + 294 WP_049399286.1 copper-sensing transcriptional repressor CsoR Antitoxin
NF392_RS03960 849972..850178 + 207 WP_023351364.1 hypothetical protein Toxin
NF392_RS03965 850315..850452 + 138 WP_002435861.1 Lmo0850 family protein -
NF392_RS03970 850508..851719 - 1212 WP_023351365.1 FtsW/RodA/SpoVE family cell cycle protein -
NF392_RS03975 852124..853194 + 1071 WP_002435813.1 D-alanine--D-alanine ligase -
NF392_RS03980 853210..854565 + 1356 WP_023351368.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(15-92)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7821.85 Da        Isoelectric Point: 4.2087

>T253175 WP_023351364.1 NZ_CP102089:849972-850178 [Staphylococcus capitis subsp. capitis]
MENGIVYVANIETIEEENQLKTRLENMIGVEKVDIDSKVGEIKVLFETPANLNSIEKEVYDSGFRVRY

Download         Length: 207 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11093.61 Da        Isoelectric Point: 6.4776

>AT253175 WP_049399286.1 NZ_CP102089:849664-849957 [Staphylococcus capitis subsp. capitis]
VTENETAHHSEQTKVNLKSRLNRIEGQVRAINRMIEDDVYCDDVLTQIRATRSALNSVATKLLDHHMKSCIMNKVNNGAQ
EEAMEELLVTFQKLIKD

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J4E3P3

Antitoxin

Source ID Structure

References