Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 1653462..1653976 Replicon chromosome
Accession NZ_CP102087
Organism Staphylococcus capitis subsp. capitis strain K1-2-2-23

Toxin (Protein)


Gene name TsdT Uniprot ID A0A1J4E3P3
Locus tag NF398_RS08095 Protein ID WP_023351364.1
Coordinates 1653462..1653668 (-) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag NF398_RS08100 Protein ID WP_049399286.1
Coordinates 1653683..1653976 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NF398_RS08075 1649075..1650430 - 1356 WP_023351368.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -
NF398_RS08080 1650446..1651516 - 1071 WP_002435813.1 D-alanine--D-alanine ligase -
NF398_RS08085 1651921..1653132 + 1212 WP_023351365.1 FtsW/RodA/SpoVE family cell cycle protein -
NF398_RS08090 1653188..1653325 - 138 WP_002435861.1 Lmo0850 family protein -
NF398_RS08095 1653462..1653668 - 207 WP_023351364.1 hypothetical protein Toxin
NF398_RS08100 1653683..1653976 - 294 WP_049399286.1 copper-sensing transcriptional repressor CsoR Antitoxin
NF398_RS08105 1654162..1655646 + 1485 WP_002435854.1 cardiolipin synthase -
NF398_RS08110 1655703..1656365 + 663 WP_023351363.1 HD domain-containing protein -
NF398_RS08115 1656424..1657296 - 873 WP_002435877.1 membrane protein insertase YidC -
NF398_RS08120 1657385..1658023 - 639 WP_023351362.1 thiamine phosphate synthase -
NF398_RS08125 1658030..1658818 - 789 WP_023351361.1 hydroxyethylthiazole kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(15-92)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7821.85 Da        Isoelectric Point: 4.2087

>T253172 WP_023351364.1 NZ_CP102087:c1653668-1653462 [Staphylococcus capitis subsp. capitis]
MENGIVYVANIETIEEENQLKTRLENMIGVEKVDIDSKVGEIKVLFETPANLNSIEKEVYDSGFRVRY

Download         Length: 207 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11093.61 Da        Isoelectric Point: 6.4776

>AT253172 WP_049399286.1 NZ_CP102087:c1653976-1653683 [Staphylococcus capitis subsp. capitis]
VTENETAHHSEQTKVNLKSRLNRIEGQVRAINRMIEDDVYCDDVLTQIRATRSALNSVATKLLDHHMKSCIMNKVNNGAQ
EEAMEELLVTFQKLIKD

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J4E3P3

Antitoxin

Source ID Structure

References