Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1418224..1418834 Replicon chromosome
Accession NZ_CP102085
Organism Mycoavidus sp. SF9855

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NQD60_RS05495 Protein ID WP_257099987.1
Coordinates 1418224..1418529 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NQD60_RS05500 Protein ID WP_257099988.1
Coordinates 1418526..1418834 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQD60_RS05465 (NQD60_05465) 1414397..1414936 - 540 WP_257099981.1 hypothetical protein -
NQD60_RS05470 (NQD60_05470) 1415107..1416261 - 1155 WP_257099982.1 hypothetical protein -
NQD60_RS05475 (NQD60_05475) 1416423..1416785 - 363 WP_257099983.1 hypothetical protein -
NQD60_RS05480 (NQD60_05480) 1416782..1417279 - 498 WP_257099984.1 hypothetical protein -
NQD60_RS05485 (NQD60_05485) 1417325..1417765 - 441 WP_257099985.1 DUF4054 domain-containing protein -
NQD60_RS05490 (NQD60_05490) 1417767..1418123 - 357 WP_257099986.1 hypothetical protein -
NQD60_RS05495 (NQD60_05495) 1418224..1418529 + 306 WP_257099987.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQD60_RS05500 (NQD60_05500) 1418526..1418834 + 309 WP_257099988.1 putative addiction module antidote protein Antitoxin
NQD60_RS05505 (NQD60_05505) 1418835..1419929 - 1095 WP_257099989.1 DUF2184 domain-containing protein -
NQD60_RS05510 (NQD60_05510) 1419940..1420440 - 501 WP_257099990.1 hypothetical protein -
NQD60_RS05515 (NQD60_05515) 1420445..1421674 - 1230 WP_257099991.1 DUF2213 domain-containing protein -
NQD60_RS05520 (NQD60_05520) 1421671..1422531 - 861 WP_257099992.1 phage minor head protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1373956..1436841 62885


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11633.28 Da        Isoelectric Point: 9.9572

>T253160 WP_257099987.1 NZ_CP102085:1418224-1418529 [Mycoavidus sp. SF9855]
MIEIIQSTTFSAWLSDLKDRQARARIQVRLDRIRNGNFGDVKPIGNGLSEARIHYGNGYRLYFLQHKKELVVLLCGGDKS
TQSRDIEQAKRIAQEWTESIL

Download         Length: 306 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11210.64 Da        Isoelectric Point: 4.4354

>AT253160 WP_257099988.1 NZ_CP102085:1418526-1418834 [Mycoavidus sp. SF9855]
MTEKFTRYDTAEYLKTDEDIAAYFDAVLEENDPQLAVQALGTIARAKGMSQIAQETGLARESLYRALSDTGNPEFATVFK
VIRALGLQLHASLPPIQYNVAG

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References