Detailed information of TA system TA025316

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-parD/RelE-CC2985
• Location: 3379499..3380061
• Replicon: chromosome
• Accession: NC_015580
• Organism: Novosphingobium sp. PP1Y

Toxin (Protein)

• Gene name: relE
• Uniprot ID: G6EDG6
• Locus tag: PP1Y_RS21975
• Protein ID: WP_007013302.1
• Coordinates: 3379499..3379792 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: F6IHT4
• Locus tag: PP1Y_RS21980
• Protein ID: WP_013834143.1
• Coordinates: 3379792..3380061 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

• Antitoxin ParD (3-67)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10792.30 Da
• Isoelectric Point: 6.2147

>T25316 WP_007013302.1 NC_015580:c3379792-3379499 [Novosphingobium sp. PP1Y]
MHLQFSPAAEADLVDIAAFIARDNVPRAFTFVDELEAACARLVDFPESGSARFDLRPGLRSRPHGSYVIFYSTLDRVIRI
ERILHGARDVGAILFSS

Nucleotide

• Length: 294 bp

>T25316 NC_015580:c3379792-3379499 [Novosphingobium sp. PP1Y]
ATGCATCTGCAGTTTTCGCCCGCGGCGGAAGCAGACCTTGTCGATATTGCCGCCTTCATCGCTCGCGACAATGTTCCGCG
GGCTTTCACCTTTGTTGACGAACTTGAAGCGGCATGTGCCAGACTTGTCGATTTCCCCGAGTCCGGGAGTGCTCGTTTCG
ACCTTCGTCCCGGGCTGCGCTCCAGACCGCACGGTAGCTATGTGATCTTCTACAGCACCCTGGACAGGGTCATTCGTATC
GAGCGTATTCTGCATGGGGCCCGCGATGTCGGCGCGATCCTCTTTTCCAGTTAG

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9558.65 Da
• Isoelectric Point: 6.4653

>AT25316 WP_013834143.1 NC_015580:c3380061-3379792 [Novosphingobium sp. PP1Y]
MPSSFTLGAHFEGFIKSQVNSGRYASASEVVRDSLRLLEEQDAMRQARLDALRAEIEHGATSGPGIPAEQAFANARKRIA
DIAAAARDS

Nucleotide

• Length: 270 bp

>AT25316 NC_015580:c3380061-3379792 [Novosphingobium sp. PP1Y]
ATGCCTTCCAGCTTTACCCTGGGTGCCCATTTCGAGGGCTTCATCAAGAGCCAGGTGAACAGCGGTCGCTACGCGTCCGC
CAGCGAGGTCGTTCGCGATAGCCTCCGCTTGCTCGAGGAACAGGACGCAATGCGTCAGGCTCGGCTCGATGCGCTGCGCG
CCGAGATCGAGCACGGCGCTACCAGCGGTCCGGGCATTCCTGCTGAGCAGGCATTCGCGAACGCACGCAAGCGGATCGCT
GATATCGCCGCCGCCGCCAGGGATAGTTGA

Structures

Toxin

• AlphaFold DB: G6EDG6

Antitoxin

• AlphaFold DB: F6IHT4