Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1343470..1344070 Replicon chromosome
Accession NZ_CP102085
Organism Mycoavidus sp. SF9855

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NQD60_RS05135 Protein ID WP_257099917.1
Coordinates 1343771..1344070 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NQD60_RS05130 Protein ID WP_257099916.1
Coordinates 1343470..1343769 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQD60_RS05090 (NQD60_05090) 1339121..1339372 - 252 WP_257099908.1 hypothetical protein -
NQD60_RS05095 (NQD60_05095) 1339402..1339602 + 201 WP_257099909.1 hypothetical protein -
NQD60_RS05100 (NQD60_05100) 1339627..1340460 + 834 WP_257099910.1 DNA adenine methylase -
NQD60_RS05105 (NQD60_05105) 1340500..1340700 + 201 WP_257099911.1 hypothetical protein -
NQD60_RS05110 (NQD60_05110) 1340715..1341569 + 855 WP_257099912.1 hypothetical protein -
NQD60_RS05115 (NQD60_05115) 1341556..1342209 + 654 WP_257099913.1 DUF6475 domain-containing protein -
NQD60_RS05120 (NQD60_05120) 1342242..1342685 + 444 WP_257099914.1 RusA family crossover junction endodeoxyribonuclease -
NQD60_RS05125 (NQD60_05125) 1342802..1343206 + 405 WP_257099915.1 hypothetical protein -
NQD60_RS05130 (NQD60_05130) 1343470..1343769 - 300 WP_257099916.1 putative addiction module antidote protein Antitoxin
NQD60_RS05135 (NQD60_05135) 1343771..1344070 - 300 WP_257099917.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NQD60_RS05140 (NQD60_05140) 1344458..1344871 + 414 WP_257099918.1 terminase small subunit protein -
NQD60_RS05145 (NQD60_05145) 1344822..1346357 + 1536 WP_257099919.1 phage terminase large subunit -
NQD60_RS05150 (NQD60_05150) 1346469..1347875 + 1407 WP_257099920.1 DUF1073 domain-containing protein -
NQD60_RS05155 (NQD60_05155) 1347961..1348668 + 708 WP_257099921.1 phage minor head protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1323143..1384924 61781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11273.90 Da        Isoelectric Point: 10.2636

>T253159 WP_257099917.1 NZ_CP102085:c1344070-1343771 [Mycoavidus sp. SF9855]
MAIELKQTEAFRKWRVRLKDERARALIASRLDRLAYGHAGDAEPVGRGISELRIHYGPGYRVYFQKRGSTIIVLLCGGNK
STQADDIKKAQRLADEWSE

Download         Length: 300 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10633.16 Da        Isoelectric Point: 5.0508

>AT253159 WP_257099916.1 NZ_CP102085:c1343769-1343470 [Mycoavidus sp. SF9855]
MTEKLTTYDPAEDLASEEATAFFMAEAFKTGDVGYIAHALGVVARAKGMSQIASQTGLSREQLYRSFSEQGNPTLKTTIK
VMKALGIELTALLPTSPAF

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References