Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2001064..2001209 Replicon chromosome
Accession NZ_CP102077
Organism Klebsiella pneumoniae strain 5589

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2001100..2001202 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2001064..2001209 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOV87_RS09655 1996194..1998254 + 2061 WP_004151449.1 oligopeptidase B -
NOV87_RS09660 1998258..1998917 - 660 WP_087616344.1 exodeoxyribonuclease X -
NOV87_RS09665 1998996..1999226 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NOV87_RS09670 1999339..1999713 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NOV87_RS09675 1999717..2000586 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NOV87_RS09680 2000603..2000941 + 339 WP_004189269.1 YebY family protein -
- 2001064..2001209 - 146 - - Antitoxin
- 2001100..2001202 + 103 - - Toxin
NOV87_RS09685 2001576..2001719 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NOV87_RS09690 2001824..2002792 - 969 WP_004151446.1 VirK/YbjX family protein -
NOV87_RS09695 2002949..2003602 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
NOV87_RS09700 2003599..2003790 - 192 WP_002911395.1 YebW family protein -
NOV87_RS09705 2003888..2004127 - 240 WP_002911393.1 YebV family protein -
NOV87_RS09710 2004243..2005676 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253146 NZ_CP102077:2001100-2001202 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253146 NZ_CP102077:c2001209-2001064 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References