Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 746762..747411 Replicon chromosome
Accession NZ_CP101990
Organism Aeromicrobium sp. zg.Y50

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NP095_RS03760 Protein ID WP_232417304.1
Coordinates 746992..747411 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NP095_RS03755 Protein ID WP_232417305.1
Coordinates 746762..746995 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP095_RS03740 (NP095_03740) 743142..743360 + 219 WP_232417308.1 hypothetical protein -
NP095_RS03745 (NP095_03745) 743455..745455 + 2001 WP_232417307.1 AAA family ATPase -
NP095_RS03750 (NP095_03750) 745520..746404 - 885 WP_232417306.1 tyrosine-type recombinase/integrase -
NP095_RS03755 (NP095_03755) 746762..746995 + 234 WP_232417305.1 Arc family DNA-binding protein Antitoxin
NP095_RS03760 (NP095_03760) 746992..747411 + 420 WP_232417304.1 type II toxin-antitoxin system VapC family toxin Toxin
NP095_RS03765 (NP095_03765) 747604..747960 + 357 WP_232417303.1 zinc ribbon domain-containing protein YjdM -
NP095_RS03770 (NP095_03770) 748049..749668 + 1620 WP_187768899.1 ATP-binding cassette domain-containing protein -
NP095_RS03775 (NP095_03775) 749796..749906 + 111 Protein_730 ATP-binding cassette domain-containing protein -
NP095_RS03780 (NP095_03780) 750258..750983 + 726 WP_232417302.1 DinB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

Arc-like DNA binding domain

(12-42)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15267.41 Da        Isoelectric Point: 4.5256

>T253073 WP_232417304.1 NZ_CP101990:746992-747411 [Aeromicrobium sp. zg.Y50]
MIVLDTNVISEIFRPQPEPRVLAWLESLTDDVAITSITLAELLAGVHRLPEGRRTTDLAAAIHAAIQPYRDTRSLLAFDE
DAAAEYAEVVVSRERAGLPISMVDAQIAAICRVNRAICATRNVKDFEATGVDVANPWRE

Download         Length: 420 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8148.23 Da        Isoelectric Point: 5.0623

>AT253073 WP_232417305.1 NZ_CP101990:746762-746995 [Aeromicrobium sp. zg.Y50]
MASIIVRGLDDSVKQRLAAQAEEHGRSMEAEVRDILTRAASRPHVGLALLEVARAVGGVEDLAIPDRADAARGVDFG

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References