253057

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4455262..4456985 Replicon chromosome
Accession NZ_CP101948
Organism Aeromonas salmonicida strain FN1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag NP805_RS20815 Protein ID WP_256685826.1
Coordinates 4455262..4455912 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag NP805_RS20820 Protein ID WP_256685828.1
Coordinates 4455912..4456985 (+) Length 358 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP805_RS20800 (NP805_20795) 4450507..4451859 + 1353 WP_256685820.1 restriction endonuclease subunit S -
NP805_RS20805 (NP805_20800) 4451856..4453235 + 1380 WP_256685822.1 DUF262 domain-containing protein -
NP805_RS20810 (NP805_20805) 4453225..4455258 + 2034 WP_256685824.1 DUF262 domain-containing protein -
NP805_RS20815 (NP805_20810) 4455262..4455912 + 651 WP_256685826.1 DUF4433 domain-containing protein Toxin
NP805_RS20820 (NP805_20815) 4455912..4456985 + 1074 WP_256685828.1 macro domain-containing protein Antitoxin
NP805_RS20825 (NP805_20820) 4457211..4460321 + 3111 WP_256685830.1 HsdR family type I site-specific deoxyribonuclease -
NP805_RS20830 (NP805_20825) 4460318..4461046 + 729 WP_256685832.1 SprT family zinc-dependent metalloprotease -
NP805_RS20835 (NP805_20830) 4461164..4461979 - 816 WP_256685834.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4445837..4464498 18661


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 24967.36 Da        Isoelectric Point: 6.4210

>T253057 WP_256685826.1 NZ_CP101948:4455262-4455912 [Aeromonas salmonicida]
MPYDYSSGLNPDKALIFRIVHRDNLPWILTHGLWAGNAPEQSDTWVHIGLAELINKRAHHPVPLAPFGVLNDYVPFYFTP
FSPMLSNIHSGRGVRQRSNDEILILVSSLHKIAELELAFLFTDSHAYYQWANFYDDLGELNRIDWPILQRRDFKRNPDDP
AKFERYQAEALVHQHCPVEALVGVVCYNEEIKTQVEQTMAQLGVARPVHVRSGWYF

Download         Length: 651 bp

Antitoxin


Download         Length: 358 a.a.        Molecular weight: 40743.83 Da        Isoelectric Point: 6.6620

>AT253057 WP_256685828.1 NZ_CP101948:4455912-4456985 [Aeromonas salmonicida]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMARYATACKRGDVVTGKMFITDTGELLGPRWIINFPTK
QHWRSPSQMAWIQEGLQELRHWLEQNHVKSIAIPPLGAGNGGLPWPEVKQAIEEALGDLDIEILLFEPSNQYQNVAKRTG
VEHLTPARALIAELVRRYWFLGMECSLLEIQKLAWFLERFIRQTAPQDPLQLHFTAHHYGPYANNLTHLLNAMDGSYLKS
DKRIPDSKPFDVIWFNDDKKQLLTTYLHTEAQDYLPALEQAAALIDGFESPYGMELLATVDWMVNQEGCEPTVEALRESL
IRWPKGGKWAQRKAKLFDDKSLRIALTRLQQSFPAYH

Download         Length: 1074 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References