Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3986503..3987163 Replicon chromosome
Accession NZ_CP101940
Organism Salmonella enterica subsp. enterica strain QA-1986 974

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag NP448_RS19650 Protein ID WP_000244756.1
Coordinates 3986750..3987163 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NP448_RS19645 Protein ID WP_000351186.1
Coordinates 3986503..3986769 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP448_RS19625 (3982432) 3982432..3983865 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
NP448_RS19630 (3984023) 3984023..3984334 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NP448_RS19635 (3984498) 3984498..3985157 + 660 WP_000250289.1 hemolysin III family protein -
NP448_RS19640 (3985273) 3985273..3986253 - 981 WP_058652990.1 tRNA-modifying protein YgfZ -
NP448_RS19645 (3986503) 3986503..3986769 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NP448_RS19650 (3986750) 3986750..3987163 + 414 WP_000244756.1 protein YgfX Toxin
NP448_RS19655 (3987216) 3987216..3987737 - 522 WP_001055885.1 flavodoxin FldB -
NP448_RS19660 (3987850) 3987850..3988746 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NP448_RS19665 (3988770) 3988770..3989483 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NP448_RS19670 (3989489) 3989489..3991222 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T253052 WP_000244756.1 NZ_CP101940:3986750-3987163 [Salmonella enterica subsp. enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT253052 WP_000351186.1 NZ_CP101940:3986503-3986769 [Salmonella enterica subsp. enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References