Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 2334268..2334844 | Replicon | chromosome |
Accession | NZ_CP101940 | ||
Organism | Salmonella enterica subsp. enterica strain QA-1986 974 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | M7RG88 |
Locus tag | NP448_RS11585 | Protein ID | WP_001131963.1 |
Coordinates | 2334557..2334844 (-) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | B5R9R5 |
Locus tag | NP448_RS11580 | Protein ID | WP_000063142.1 |
Coordinates | 2334268..2334570 (-) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NP448_RS11565 (2330778) | 2330778..2332928 | + | 2151 | WP_000379927.1 | pyruvate/proton symporter BtsT | - |
NP448_RS11570 (2333023) | 2333023..2333226 | + | 204 | WP_000460616.1 | YbdD/YjiX family protein | - |
NP448_RS11575 (2333237) | 2333237..2334193 | + | 957 | WP_000187839.1 | GTPase | - |
NP448_RS11580 (2334268) | 2334268..2334570 | - | 303 | WP_000063142.1 | BrnA antitoxin family protein | Antitoxin |
NP448_RS11585 (2334557) | 2334557..2334844 | - | 288 | WP_001131963.1 | BrnT family toxin | Toxin |
NP448_RS11590 (2335113) | 2335113..2336027 | - | 915 | WP_000290512.1 | restriction endonuclease | - |
NP448_RS11595 (2336225) | 2336225..2339734 | + | 3510 | WP_001043484.1 | type I restriction-modification system endonuclease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11294.80 Da Isoelectric Point: 9.5894
>T253044 WP_001131963.1 NZ_CP101940:c2334844-2334557 [Salmonella enterica subsp. enterica]
MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYENGEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERNRYEHG
MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYENGEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERNRYEHG
Download Length: 288 bp
Antitoxin
Download Length: 101 a.a. Molecular weight: 11373.96 Da Isoelectric Point: 10.1293
>AT253044 WP_000063142.1 NZ_CP101940:c2334570-2334268 [Salmonella enterica subsp. enterica]
MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDGQWSEAVRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK
MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDGQWSEAVRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK
Download Length: 303 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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