Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-Xress/RelE-YozG |
| Location | 3720742..3721388 | Replicon | chromosome |
| Accession | NC_015577 | ||
| Organism | Treponema azotonutricium ZAS-9 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | F5YFN9 |
| Locus tag | TREAZ_RS16505 | Protein ID | WP_015713041.1 |
| Coordinates | 3721020..3721388 (+) | Length | 123 a.a. |
Antitoxin (Protein)
| Gene name | Xress | Uniprot ID | - |
| Locus tag | TREAZ_RS16500 | Protein ID | WP_015713040.1 |
| Coordinates | 3720742..3720963 (+) | Length | 74 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| TREAZ_RS17585 | 3715942..3716319 | + | 378 | WP_015713025.1 | hypothetical protein | - |
| TREAZ_RS16435 | 3716391..3716900 | + | 510 | WP_015713026.1 | terminase small subunit | - |
| TREAZ_RS16440 | 3717043..3717477 | + | 435 | WP_015713027.1 | hypothetical protein | - |
| TREAZ_RS16445 | 3717564..3717743 | - | 180 | WP_015713028.1 | hypothetical protein | - |
| TREAZ_RS16450 | 3717718..3717900 | - | 183 | WP_015713029.1 | DUF2292 domain-containing protein | - |
| TREAZ_RS16455 | 3717890..3718210 | - | 321 | WP_015713030.1 | integration host factor subunit beta | - |
| TREAZ_RS16460 | 3718203..3718385 | - | 183 | WP_015713031.1 | hypothetical protein | - |
| TREAZ_RS16465 | 3718378..3718608 | - | 231 | WP_015713032.1 | hypothetical protein | - |
| TREAZ_RS16470 | 3718605..3718880 | - | 276 | WP_015713033.1 | hypothetical protein | - |
| TREAZ_RS16475 | 3718877..3719167 | - | 291 | WP_015713034.1 | hypothetical protein | - |
| TREAZ_RS16480 | 3719164..3719460 | - | 297 | WP_015713035.1 | hypothetical protein | - |
| TREAZ_RS16485 | 3719618..3719908 | - | 291 | WP_015713036.1 | hypothetical protein | - |
| TREAZ_RS16490 | 3720038..3720241 | - | 204 | WP_015713037.1 | hypothetical protein | - |
| TREAZ_RS16495 | 3720238..3720450 | - | 213 | WP_015713038.1 | hypothetical protein | - |
| TREAZ_RS16500 | 3720742..3720963 | + | 222 | WP_015713040.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| TREAZ_RS16505 | 3721020..3721388 | + | 369 | WP_015713041.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| TREAZ_RS16510 | 3721385..3721591 | + | 207 | WP_015713042.1 | hypothetical protein | - |
| TREAZ_RS16515 | 3721887..3722090 | - | 204 | WP_015713043.1 | helix-turn-helix domain-containing protein | - |
| TREAZ_RS16520 | 3722237..3722959 | + | 723 | WP_015713044.1 | hypothetical protein | - |
| TREAZ_RS16525 | 3722963..3723439 | - | 477 | WP_015713045.1 | S-ribosylhomocysteine lyase | - |
| TREAZ_RS16530 | 3723441..3724151 | - | 711 | WP_015713046.1 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | - |
| TREAZ_RS16535 | 3724161..3725321 | - | 1161 | WP_015713047.1 | sensor domain-containing diguanylate cyclase | - |
| TREAZ_RS17590 | 3725321..3725890 | - | 570 | WP_052297708.1 | hypothetical protein | - |
| TREAZ_RS16545 | 3726032..3726379 | - | 348 | WP_015713049.1 | YraN family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13700.60 Da Isoelectric Point: 10.0181
>T25302 WP_015713041.1 NC_015577:3721020-3721388 [Treponema azotonutricium ZAS-9]
MRIFKTKRFTKLSDKAGITDTDLITAAEEVNRGEYEADLGGGVFKKRVARVGAGKSGGYRVILFFRQDERLIFSYVFAKS
NRGNIDDAELRAFRATAKGDLEYTEDQMNAFVKKGLYKELGA
MRIFKTKRFTKLSDKAGITDTDLITAAEEVNRGEYEADLGGGVFKKRVARVGAGKSGGYRVILFFRQDERLIFSYVFAKS
NRGNIDDAELRAFRATAKGDLEYTEDQMNAFVKKGLYKELGA
Download Length: 369 bp
>T25302 NC_015577:3721020-3721388 [Treponema azotonutricium ZAS-9]
ATGCGTATATTTAAGACGAAGCGGTTTACCAAGCTTTCAGATAAGGCGGGGATCACCGATACAGACCTGATCACCGCCGC
AGAGGAAGTGAACCGGGGAGAGTATGAGGCCGACTTAGGCGGGGGAGTATTCAAGAAGCGAGTAGCTCGGGTAGGGGCTG
GAAAGTCTGGGGGCTATCGGGTTATCCTGTTTTTTCGGCAAGATGAACGGCTGATTTTTTCCTATGTTTTTGCCAAGTCA
AACCGGGGGAATATAGACGATGCTGAATTGAGAGCGTTTAGGGCTACCGCAAAAGGGGACCTTGAATATACCGAGGATCA
AATGAACGCCTTTGTAAAAAAGGGTTTGTATAAGGAGTTAGGAGCATGA
ATGCGTATATTTAAGACGAAGCGGTTTACCAAGCTTTCAGATAAGGCGGGGATCACCGATACAGACCTGATCACCGCCGC
AGAGGAAGTGAACCGGGGAGAGTATGAGGCCGACTTAGGCGGGGGAGTATTCAAGAAGCGAGTAGCTCGGGTAGGGGCTG
GAAAGTCTGGGGGCTATCGGGTTATCCTGTTTTTTCGGCAAGATGAACGGCTGATTTTTTCCTATGTTTTTGCCAAGTCA
AACCGGGGGAATATAGACGATGCTGAATTGAGAGCGTTTAGGGCTACCGCAAAAGGGGACCTTGAATATACCGAGGATCA
AATGAACGCCTTTGTAAAAAAGGGTTTGTATAAGGAGTTAGGAGCATGA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8414.81 Da Isoelectric Point: 9.2911
>AT25302 WP_015713040.1 NC_015577:3720742-3720963 [Treponema azotonutricium ZAS-9]
MTTVEKIRVLLARRNIPEAELARRLGKTPQNFNRKMKVERFTEEDLEAIAKALNCTVIQAVPVFRMNESGEEI
MTTVEKIRVLLARRNIPEAELARRLGKTPQNFNRKMKVERFTEEDLEAIAKALNCTVIQAVPVFRMNESGEEI
Download Length: 222 bp
>AT25302 NC_015577:3720742-3720963 [Treponema azotonutricium ZAS-9]
ATGACTACAGTTGAGAAAATCAGGGTCTTGCTTGCTCGGCGGAATATTCCAGAGGCGGAACTTGCCCGGAGGCTTGGAAA
AACCCCGCAAAACTTTAATCGCAAAATGAAAGTCGAAAGGTTTACAGAGGAGGATCTTGAAGCGATTGCAAAGGCTCTGA
ATTGTACGGTCATTCAGGCGGTCCCTGTTTTTCGCATGAATGAAAGCGGCGAGGAGATATGA
ATGACTACAGTTGAGAAAATCAGGGTCTTGCTTGCTCGGCGGAATATTCCAGAGGCGGAACTTGCCCGGAGGCTTGGAAA
AACCCCGCAAAACTTTAATCGCAAAATGAAAGTCGAAAGGTTTACAGAGGAGGATCTTGAAGCGATTGCAAAGGCTCTGA
ATTGTACGGTCATTCAGGCGGTCCCTGTTTTTCGCATGAATGAAAGCGGCGAGGAGATATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|