Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2220269..2220537 Replicon chromosome
Accession NZ_CP101925
Organism Escherichia coli strain Seattle 1946

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2220397..2220499 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2220269..2220537 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP429_RS10390 2216821..2217483 - 663 WP_000944256.1 exodeoxyribonuclease X -
NP429_RS10395 2217507..2218163 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
NP429_RS10400 2218266..2218496 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NP429_RS10405 2218635..2219009 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NP429_RS10410 2219013..2219885 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
NP429_RS10415 2219898..2220239 + 342 WP_000984819.1 YebY family protein -
- 2220269..2220537 - 269 - - Antitoxin
- 2220397..2220499 + 103 - - Toxin
NP429_RS10420 2220634..2221290 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
NP429_RS10425 2221291..2221482 - 192 WP_001317886.1 YebW family protein -
NP429_RS10430 2221587..2221823 - 237 WP_001295499.1 YebV family protein -
NP429_RS10435 2221941..2223380 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252992 NZ_CP101925:2220397-2220499 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT252992 NZ_CP101925:c2220537-2220269 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References