Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 1118569..1119224 Replicon chromosome
Accession NZ_CP101914
Organism Oceanobacillus jeddahense strain QA-1986 374

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NP439_RS05610 Protein ID WP_040983616.1
Coordinates 1118862..1119224 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag NP439_RS05605 Protein ID WP_040983614.1
Coordinates 1118569..1118856 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP439_RS05585 (NP439_05585) 1114074..1114859 - 786 WP_256709128.1 rhomboid family intramembrane serine protease -
NP439_RS05590 (NP439_05590) 1114988..1115341 + 354 WP_256709129.1 holo-ACP synthase -
NP439_RS05595 (NP439_05595) 1115427..1116941 + 1515 WP_256709130.1 NAD(P)H-hydrate dehydratase -
NP439_RS05600 (NP439_05600) 1117007..1118044 + 1038 WP_256709131.1 DUF4367 domain-containing protein -
NP439_RS05605 (NP439_05605) 1118569..1118856 + 288 WP_040983614.1 hypothetical protein Antitoxin
NP439_RS05610 (NP439_05610) 1118862..1119224 + 363 WP_040983616.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NP439_RS05615 (NP439_05615) 1119616..1120329 + 714 WP_256709132.1 HAD family hydrolase -
NP439_RS05620 (NP439_05620) 1120790..1121659 + 870 WP_256709133.1 RsbT co-antagonist protein RsbRA -
NP439_RS05625 (NP439_05625) 1121663..1122019 + 357 WP_040983621.1 STAS domain-containing protein -
NP439_RS05630 (NP439_05630) 1122023..1122424 + 402 WP_040983623.1 anti-sigma regulatory factor -
NP439_RS05635 (NP439_05635) 1122605..1123618 + 1014 WP_256709134.1 PP2C family protein-serine/threonine phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13494.56 Da        Isoelectric Point: 7.0142

>T252903 WP_040983616.1 NZ_CP101914:1118862-1119224 [Oceanobacillus jeddahense]
VIVQRGEVYFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFDRNSVILLEQI
RTLDKQRLTDKITKLDKEMMEKIDQSLEISLGLRDVYSNN

Download         Length: 363 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11045.45 Da        Isoelectric Point: 4.3531

>AT252903 WP_040983614.1 NZ_CP101914:1118569-1118856 [Oceanobacillus jeddahense]
MAENKEEILVKIPKNLLSEVDGLMKYENSSDLNDFICEATQIYLNHKKEEHLQRFHETMQRGYEEMARINLTIASEAFQA
EEEAEITLERSVIGV

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References