Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 4215577..4216616 | Replicon | chromosome |
| Accession | NZ_CP101910 | ||
| Organism | Pseudomonas putida strain ATCC 12633 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | NP430_RS19005 | Protein ID | WP_016498726.1 |
| Coordinates | 4216041..4216616 (+) | Length | 192 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | NP430_RS19000 | Protein ID | WP_016498727.1 |
| Coordinates | 4215577..4216044 (+) | Length | 156 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NP430_RS18980 (NP430_18980) | 4211186..4212259 | + | 1074 | WP_016498730.1 | microcin C ABC transporter permease YejB | - |
| NP430_RS18985 (NP430_18985) | 4212261..4213280 | + | 1020 | WP_016498729.1 | ABC transporter permease | - |
| NP430_RS18990 (NP430_18990) | 4213282..4214892 | + | 1611 | WP_016498728.1 | ABC transporter ATP-binding protein | - |
| NP430_RS18995 (NP430_18995) | 4215131..4215394 | + | 264 | Protein_3722 | DUF3077 domain-containing protein | - |
| NP430_RS19000 (NP430_19000) | 4215577..4216044 | + | 468 | WP_016498727.1 | excisionase family DNA-binding protein | Antitoxin |
| NP430_RS19005 (NP430_19005) | 4216041..4216616 | + | 576 | WP_016498726.1 | PIN domain-containing protein | Toxin |
| NP430_RS19010 (NP430_19010) | 4216839..4219769 | + | 2931 | WP_016498725.1 | aminotransferase | - |
| NP430_RS19015 (NP430_19015) | 4219773..4221008 | - | 1236 | WP_041167657.1 | NAD(P)/FAD-dependent oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 4195705..4220996 | 25291 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21599.76 Da Isoelectric Point: 5.0339
>T252885 WP_016498726.1 NZ_CP101910:4216041-4216616 [Pseudomonas putida]
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSAGIHDEWKRNLLLNRPDLTPEHVDRTSSLMDAAVPDALVTDY
DSPVEGLDLPDEDDRHVLAAAIKCNASVIVTFNLKDFPKSVLGVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRISLKN
PPHSVQQYLDRLLQQKLPETVKLLSGFKFLL
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSAGIHDEWKRNLLLNRPDLTPEHVDRTSSLMDAAVPDALVTDY
DSPVEGLDLPDEDDRHVLAAAIKCNASVIVTFNLKDFPKSVLGVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRISLKN
PPHSVQQYLDRLLQQKLPETVKLLSGFKFLL
Download Length: 576 bp
Antitoxin
Download Length: 156 a.a. Molecular weight: 17220.62 Da Isoelectric Point: 6.1059
>AT252885 WP_016498727.1 NZ_CP101910:4215577-4216044 [Pseudomonas putida]
MTTANLSRNVLPDEKEIAVSVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDEAVIPHTKTGRHRRVRFSDLVAYKDQRDGVSRAAMDALAAQAQELKMGYE
MTTANLSRNVLPDEKEIAVSVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPHLVKLLDEAVIPHTKTGRHRRVRFSDLVAYKDQRDGVSRAAMDALAAQAQELKMGYE
Download Length: 468 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|