Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1045613..1046199 Replicon chromosome
Accession NZ_CP101910
Organism Pseudomonas putida strain ATCC 12633

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag NP430_RS04570 Protein ID WP_041167864.1
Coordinates 1045613..1045906 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag NP430_RS04575 Protein ID WP_016501413.1
Coordinates 1045903..1046199 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP430_RS04545 (NP430_04545) 1041214..1042068 + 855 WP_016501419.1 putative selenate ABC transporter substrate-binding protein -
NP430_RS04550 (NP430_04550) 1042065..1042874 + 810 WP_016501418.1 ATP-binding cassette domain-containing protein -
NP430_RS04555 (NP430_04555) 1042868..1043695 + 828 WP_016501417.1 ABC transporter permease -
NP430_RS04560 (NP430_04560) 1043692..1044459 + 768 WP_016501416.1 phosphonate ABC transporter, permease protein PhnE -
NP430_RS04565 (NP430_04565) 1044496..1045389 - 894 WP_016501415.1 bestrophin family ion channel -
NP430_RS04570 (NP430_04570) 1045613..1045906 + 294 WP_041167864.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NP430_RS04575 (NP430_04575) 1045903..1046199 + 297 WP_016501413.1 putative addiction module antidote protein Antitoxin
NP430_RS04580 (NP430_04580) 1046210..1046689 - 480 WP_016501412.1 GNAT family N-acetyltransferase -
NP430_RS04585 (NP430_04585) 1046842..1047489 - 648 WP_016501411.1 serine protease -
NP430_RS04590 (NP430_04590) 1047822..1048244 + 423 WP_016501410.1 VOC family protein -
NP430_RS04595 (NP430_04595) 1048646..1050061 + 1416 WP_016501409.1 FAD-binding oxidoreductase -
NP430_RS04600 (NP430_04600) 1050141..1050638 + 498 WP_016501408.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10727.54 Da        Isoelectric Point: 10.3109

>T252880 WP_041167864.1 NZ_CP101910:1045613-1045906 [Pseudomonas putida]
MFLVEQTESFAACLSSLRDLRARLAIGRRLERAAGGNLGDFKWLGGDIGELRIDVAAGYRVYFTQKGERLVLLLVGGDKS
TQAADILKARKLLKEMK

Download         Length: 294 bp

>T252880 NZ_CP101910:1045613-1045906 [Pseudomonas putida]
ATGTTTCTCGTTGAACAGACGGAAAGCTTTGCCGCTTGCCTATCGAGCTTGAGAGATTTGAGGGCCAGGCTGGCGATAGG
TCGTAGGCTGGAGCGAGCAGCGGGGGGCAATCTTGGTGACTTCAAGTGGCTTGGAGGCGATATTGGTGAGCTTCGCATCG
ACGTAGCTGCCGGTTATCGCGTCTATTTCACGCAAAAGGGGGAGAGGTTGGTTTTACTGCTGGTCGGCGGCGACAAGTCC
ACCCAGGCCGCCGACATCCTCAAAGCCAGAAAGCTGCTGAAGGAGATGAAATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10668.30 Da        Isoelectric Point: 5.6864

>AT252880 WP_016501413.1 NZ_CP101910:1045903-1046199 [Pseudomonas putida]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLR
VIRALGVDLLVQPQAMTR

Download         Length: 297 bp

>AT252880 NZ_CP101910:1045903-1046199 [Pseudomonas putida]
ATGAGCGAAAAATTGATCCCGTTTGATATGGCAGCCTTGTTGAGCAGCGATGAGGCAATCAGTGAATACCTTAGCCAGGT
GCTATCAGATGGCGATACCGAGGAAATCATTCGAGCACTTGGACATATCGCTCGTGCACGGGGCATGACACATATTGCTA
CGGAGAGTGGGCTGGGTAGAGAAAGCCTGTACAAGGCGCTGAGCCCTGGCGCGAAGCCTCGTTTTGACACGGTATTGAGG
GTCATTCGTGCTCTGGGGGTGGACCTTCTCGTTCAGCCACAGGCAATGACCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References