Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-higA/HigB-HigA
Location 365316..365956 Replicon chromosome
Accession NZ_CP101910
Organism Pseudomonas putida strain ATCC 12633

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NP430_RS01530 Protein ID WP_231859021.1
Coordinates 365316..365441 (+) Length 42 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NP430_RS01535 Protein ID WP_016497583.1
Coordinates 365483..365956 (+) Length 158 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP430_RS01515 (NP430_01515) 361483..362205 - 723 WP_016497580.1 response regulator -
NP430_RS01520 (NP430_01520) 362346..364643 + 2298 WP_016497581.1 TonB-dependent siderophore receptor -
NP430_RS01525 (NP430_01525) 364935..365141 - 207 WP_016497582.1 DUF3079 domain-containing protein -
NP430_RS01530 (NP430_01530) 365316..365441 + 126 WP_231859021.1 type II toxin-antitoxin system HigB family toxin Toxin
NP430_RS01535 (NP430_01535) 365483..365956 + 474 WP_016497583.1 transcriptional regulator Antitoxin
NP430_RS01540 (NP430_01540) 366366..367664 + 1299 WP_016497584.1 hypothetical protein -
NP430_RS01545 (NP430_01545) 367668..368246 + 579 WP_016497585.1 hypothetical protein -
NP430_RS01550 (NP430_01550) 368448..369221 - 774 WP_016497586.1 FAD-dependent thymidylate synthase -
NP430_RS01555 (NP430_01555) 369218..370108 - 891 WP_041167494.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(3-35)

Antitoxin

Antitoxin HigA

(43-154)


Sequences

Toxin        


Download         Length: 42 a.a.        Molecular weight: 4864.70 Da        Isoelectric Point: 9.8495

>T252879 WP_231859021.1 NZ_CP101910:365316-365441 [Pseudomonas putida]
MRVKKNECRHIACLNARTGTLYIKAILSHAEYDKWCRSDIR

Download         Length: 126 bp

Antitoxin


Download         Length: 158 a.a.        Molecular weight: 17170.65 Da        Isoelectric Point: 4.6719

>AT252879 WP_016497583.1 NZ_CP101910:365483-365956 [Pseudomonas putida]
MKRAKIEANGLDAFIANISPMLDGLNTQMATMAQLLAACHDPIKDDAELQARMALIDELYSHADSEGHAAARFAEMVADR
VYEYESESVLVPFASQAEALAFLLSDRGVKQKDLSAIATQSAVSEILNNKRKMTVAQVKGFAEFFSVPVEFFMHGVV

Download         Length: 474 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References