Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1904882..1905027 Replicon chromosome
Accession NZ_CP101877
Organism Klebsiella pneumoniae strain KPA1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1904918..1905020 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1904882..1905027 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NNX43_RS09250 1900012..1902072 + 2061 WP_094083900.1 oligopeptidase B -
NNX43_RS09255 1902076..1902735 - 660 WP_002911407.1 exodeoxyribonuclease X -
NNX43_RS09260 1902814..1903044 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NNX43_RS09265 1903157..1903531 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NNX43_RS09270 1903535..1904404 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
NNX43_RS09275 1904421..1904759 + 339 WP_009307539.1 YebY family protein -
- 1904882..1905027 - 146 - - Antitoxin
- 1904918..1905020 + 103 - - Toxin
NNX43_RS09280 1905396..1905539 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NNX43_RS09285 1905644..1906612 - 969 WP_004151446.1 VirK/YbjX family protein -
NNX43_RS09290 1906769..1907422 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
NNX43_RS09295 1907419..1907610 - 192 WP_002911395.1 YebW family protein -
NNX43_RS09300 1907708..1907947 - 240 WP_002911393.1 YebV family protein -
NNX43_RS09305 1908063..1909496 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252834 NZ_CP101877:1904918-1905020 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252834 NZ_CP101877:c1905027-1904882 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References