Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3254760..3256279 Replicon chromosome
Accession NZ_CP101847
Organism Xanthomonas oryzae pv. oryzae strain YNCX

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag NO935_RS15005 Protein ID WP_011259680.1
Coordinates 3254760..3255683 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag NO935_RS15010 Protein ID WP_011409027.1
Coordinates 3255680..3256279 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NO935_RS14975 (NO935_14975) 3250359..3250511 + 153 Protein_2881 SAM-dependent methyltransferase -
NO935_RS14980 (NO935_14980) 3250623..3251999 + 1377 WP_261945546.1 IS5 family transposase -
NO935_RS14985 (NO935_14985) 3252019..3252551 + 533 Protein_2883 protein N-lysine methyltransferase family protein -
NO935_RS14990 (NO935_14990) 3252568..3253077 - 510 WP_011259678.1 hypothetical protein -
NO935_RS14995 (NO935_14995) 3253502..3253744 - 243 WP_011259679.1 hypothetical protein -
NO935_RS15000 (NO935_15000) 3254210..3254680 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
NO935_RS15005 (NO935_15005) 3254760..3255683 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
NO935_RS15010 (NO935_15010) 3255680..3256279 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
NO935_RS15015 (NO935_15015) 3256662..3256934 + 273 WP_230455482.1 FaeA/PapI family transcriptional regulator -
NO935_RS15020 (NO935_15020) 3256966..3257454 + 489 WP_027703988.1 BrxE family protein -
NO935_RS15025 (NO935_15025) 3257968..3257969 - 2 WP_113091170.1 IS5 family transposase -
NO935_RS15030 (NO935_15030) 3258375..3259408 - 1034 Protein_2892 IS630 family transposase -
NO935_RS15035 (NO935_15035) 3259907..3260197 + 291 WP_011409031.1 hypothetical protein -
NO935_RS15040 (NO935_15040) 3260178..3260552 + 375 WP_229002607.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3250623..3251999 1376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T252767 WP_011259680.1 NZ_CP101847:c3255683-3254760 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT252767 WP_011409027.1 NZ_CP101847:c3256279-3255680 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References