Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2006058..2006202 | Replicon | chromosome |
| Accession | NZ_CP101835 | ||
| Organism | Klebsiella pneumoniae strain GN4549 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2006094..2006196 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2006058..2006202 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NPH93_RS09830 (NPH93_09830) | 2001188..2003248 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| NPH93_RS09835 (NPH93_09835) | 2003252..2003911 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| NPH93_RS09840 (NPH93_09840) | 2003990..2004220 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NPH93_RS09845 (NPH93_09845) | 2004333..2004707 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NPH93_RS09850 (NPH93_09850) | 2004711..2005580 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| NPH93_RS09855 (NPH93_09855) | 2005597..2005935 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2006058..2006202 | - | 145 | - | - | Antitoxin |
| - | 2006094..2006196 | + | 103 | - | - | Toxin |
| NPH93_RS09860 (NPH93_09860) | 2006329..2006610 | - | 282 | Protein_1927 | tyrosine-type recombinase/integrase | - |
| NPH93_RS09865 (NPH93_09865) | 2006687..2007166 | + | 480 | WP_032419797.1 | lysis protein | - |
| NPH93_RS09870 (NPH93_09870) | 2007621..2007816 | + | 196 | Protein_1929 | DNA polymerase V | - |
| NPH93_RS09875 (NPH93_09875) | 2007955..2009460 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| NPH93_RS09880 (NPH93_09880) | 2009710..2010138 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NPH93_RS09885 (NPH93_09885) | 2010148..2010429 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T252747 NZ_CP101835:2006094-2006196 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT252747 NZ_CP101835:c2006202-2006058 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
